The American Journal of Surgery
Volume 187, Issue 1 , Pages 64-68 , January 2004

Impact of neoadjuvant therapy of perioperative morbidity in patients with esophageal cancer

  • Andreas Imdahl, M.D.

      Affiliations

    • Department of Surgery, Division of General Surgery, University Hospital of Freiburg, Hugsterstrasse 55, D-79106 Freiburg, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 761-2702401; fax: +49 761-2702804.
    • ,
  • Ulrich Schöffel, M.D.

      Affiliations

    • Department of Surgery, Division of General Surgery, University Hospital of Freiburg, Hugsterstrasse 55, D-79106 Freiburg, Germany
    • ,
  • Günther Ruf, M.D.

      Affiliations

    • Department of Surgery, Division of General Surgery, University Hospital of Freiburg, Hugsterstrasse 55, D-79106 Freiburg, Germany

Received 15 August 2002 ,Revised 12 December 2002

References 

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  2. Vogel SB, Medenhall WM, Sombeck MD, et al.  Downstaging of esophageal cancer after preoperative radiation and chemotherapy. Ann Surg. 1995;221:685–695
  3. Walsh TN, Noonan N, Hollywood D, et al.  A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Engl J Med. 1996;335:462–467
  4. Kelsen D. Preoperative chemoradiotherapy for esophageal cancer. J Clin Oncol. 2001;19:283–285
  5. Duhaylongsod FG, Gottfried MR, Iglehart JD, et al.  The significance of c-erb B2 and p53 immunoreactivity in patients with adenocarcinoma of the esophagus. Ann Surg. 1995;221:677–684
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  8. Bosset JF, Gignoux M, Triboulet JP, et al.  Chemoradiotherapy followed by surgery compared with surgery alone in squamous cell carcinoma of the esophagus. N Engl J Med. 1997;337:161–167
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  10. Girling J. the Medical Research Council Esophageal Cancer Working Party. Surgical resection with or without preoperative chemotherapy in esophageal cancer (a randomized controlled trial). Lancet. 2002;359:1727–1733
  11. Kelson DP, Ginsberg P, Pajak TF, et al.  Chemotherapy followed by surgery compared with surgery alone for localized esophageal cancer. N Engl J Med. 1998;339:1979–1984
  12. Imdahl A, Bognar G, Schulte-Mönting J, et al.  Predictive factors for response to neoadjuvant therapy in patients with oesophageal cancer. Eur J Cardiothorac Surg. 2002;21:657–663
  13. Stein HJ, Brucher BL, Sendler A, Siewert JR. Esophageal cancer (patient evaluation and pre-treatment staging). Surg Oncol. 2001;10:103–111
  14. Bolton JS, Fuhrman GM. Transhiatal esophagectomy for carcinoma of the thoracic esophagus. In:  Wanebo HJ editors. Surgery for gastrointestinal cancer. New York: Lippincot-Raven; 1996;p. 229–240
  15. Begg CB, Cramer LD, Hoskins WJ, et al.  Impact of hospital volume on operative mortality for major cancer surgery. JAMA. 1998;280:1747–1751
  16. Mafune K, Tanaka Y. Influence of multimodal therapy on the cellular immunity of patients with esophageal cancer. Ann Surg Oncol. 2000;7:609–616
  17. Bartels H, Stein HJ, Siewert JR. Preoperative risk analysis and postoperative mortality of oesophagectomy for resectable oesophageal cancer. Br J Surg. 1998;85:840–844

PII: S0002-9610(03)00440-9

doi: 10.1016/j.amjsurg.2002.12.004

The American Journal of Surgery
Volume 187, Issue 1 , Pages 64-68 , January 2004

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