The American Journal of Surgery
Volume 192, Issue 4 , Pages 516-519 , October 2006

Accuracy of intraoperative imprint cytology of sentinel lymph nodes in breast cancer

Presented at the 7th Annual Meeting of the American Society of Breast Surgeons, Baltimore, Maryland, April 5–9, 2006

  • Matthew S. Pugliese, M.D.

      Affiliations

    • Department of Surgery, Comprehensive Breast Cancer Program, Swedish Cancer Institute, Seattle, WA, USA
    • ,
  • Jennifer R. Kohr, M.D.

      Affiliations

    • Department of Surgery, Comprehensive Breast Cancer Program, Swedish Cancer Institute, Seattle, WA, USA
    • ,
  • Kimberly H. Allison, M.D.

      Affiliations

    • Department of Anatomic Pathology, University of Washington Medical Center, 1959 NE Pacific, Seattle, WA 98122, USA
    • ,
  • Nan Ping Wang, M.D., Ph.D.

      Affiliations

    • Department of Pathology, Comprehensive Breast Cancer Program, Swedish Cancer Institute, Seattle, WA, USA
    • ,
  • Ronald J. Tickman, M.D.

      Affiliations

    • Department of Pathology, Comprehensive Breast Cancer Program, Swedish Cancer Institute, Seattle, WA, USA
    • ,
  • J. David Beatty, M.D.

      Affiliations

    • Department of Surgery, Comprehensive Breast Cancer Program, Swedish Cancer Institute, Seattle, WA, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-206-215-6410; fax: +1-206-215-6401.

Received 5 April 2006 ,Revised 31 May 2006

References 

  1. Morrell RM , Halyard MY , Schild SE , et al.   Breast cancer-related lymphedema . Mayo Clin Proc . 2005;80:1480–1484
  2. Wilke LG , McCall LM , Posther KE , et al.   Surgical complications associated with sentinel lymph node biopsy: results from a prospective international cooperative group trial . Ann Surg Oncol . 2006;12:491–500
  3. Motomura K , Inaji H , Komoike Y , et al.   Intraoperative sentinel lymph node examination by imprint cytology and frozen sectioning during breast surgery . Br J Surg . 2000;87:597–601
  4. Diest PJ , Torrenga H , Borgstein PJ , et al.   Reliability of intraoperative frozen section and imprint cytological investigation of sentinel lymph nodes in breast cancer . Histopathology . 1999;35:14–18
  5. Menes TS , Tartter PI , Mizrachi H , et al.   Touch preparation or frozen section of sentinel lymph node metastases from breast cancer . Ann Surg Oncol . 2003;10:1166–1170
  6. Fitzgibbons PL , Page DL , Weaver D , et al.   Prognostic factors in breast cancer (College of American Pathologists Consensus Statement, 1999) . Arch Pathol Lab Med . 2000;124:966–978
  7. Singletary SE , Alfred C , Ashley P , et al.   Revision of the American Joint Committee on Cancer staging system for breast cancer . J Clin Oncol . 2002;20:3628–3636
  8. Giuliano AE , Kirgan DM , Guenther JM , et al.   Lymphatic mapping and sentinel lymphadenectomy for breast cancer . Ann Surg . 1994;220:391–398
  9. Albertini JJ , Lyman GH , Cox C , et al.   Lymphatic mapping and sentinel node biopsy in the patient with breast cancer . JAMA . 1996;276:1818–1822
  10. Kelley MC , Hansen N , McMasters KM . Lymphatic mapping and sentinel lymphadenectomy for breast cancer . Am J Surg . 2004;188:49–61
  11. Nasser IA , Lee AK , Bosari S , et al.   Occult axillary lymph node metastases in “node-negative” breast carcinoma . Hum Pathol . 1993;24:950–957
  12. Susnik B , Frkovic-Grazio S , Bracko M . Occult micrometastases in axillary lymph nodes predict subsequent distant metastases in stage I breast cancer: a case-control study with 15-year follow-up . Ann Surg Oncol . 2004;11:568–572
  13. Singletary ES . Early-stage invasive breast cancer: isolated tumor cells in axillary lymph nodes, peripheral blood, and bone marrow . Gen Surg News . 2006;33:17–20
  14. Kane JM , Edge SB , Winston JS , et al.   Intraoperative pathologic evaluation of a breast cancer sentinel lymph node biopsy as a determinant for synchronous axillary lymph node dissection . Ann Surg Oncol . 2001;8:361–367
  15. Shiver SA , Creager AJ , Geisinger K , et al.   Intraoperative analysis of sentinel lymph nodes by imprint cytology for cancer of the breast . Am J Surg . 2002;184:424–427
  16. Mullenix PS , Carter PL , Martin MJ , et al.   Predictive value of intraoperative touch preparation analysis of sentinel lymph nodes for axillary metastasis in breast cancer . Am J Surg . 2003;185:420–424
  17. Karamlou T , Johnson NM , Chan B , et al.   Accuracy of intraoperative touch imprint cytologic analysis of sentinel lymph nodes in breast cancer . Am J Surg . 2003;185:425–428
  18. Nagashima T , Suzuki M , Yagata H , et al.   Intraoperative cytologic diagnosis of sentinel node metastases in breast cancer . Acta Cytol . 2003;47:1028–1032
  19. Zgajnar J , Frkovic-Grazio S , Besic N , et al.   Low sensitivity of the touch imprint cytology of the sentinel lymph node in breast cancer patients—results of a large series . J Surg Oncol . 2004;85:82–86
  20. Ravichandran D , Kocjan G , Falzon M , et al.   Imprint cytology of the sentinel lymph node in the assessment of axillary node status in breast carcinoma . Eur J Surg Oncol . 2004;30:238–242
  21. Forbes RC , Pitchford C , Simpson JF , et al.   Selective use of intraoperative touch prep analysis of sentinel nodes in breast cancer . Am Surg . 2005;71:955–960
  22. Cserni G . Effect of increasing the surface sampled by imprint cytology on the intraoperative assessment of axillary sentinel lymph nodes in breast cancer patients . Am Surg . 2003;69:419–423

PII: S0002-9610(06)00423-5

doi: 10.1016/j.amjsurg.2006.05.014

The American Journal of Surgery
Volume 192, Issue 4 , Pages 516-519 , October 2006

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