The American Journal of Surgery
Volume 193, Issue 1 , Pages 21-25 , January 2007

Total splenic vein thrombosis after laparoscopic splenectomy: a possible candidate for treatment

Presented at the Annual Meeting of the Society of American Gastrointestinal Endoscopic Surgeons (SAGES), Hollywood, FL, April 13–16, 2005

  • Masataka Ikeda, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • Corresponding Author InformationCorresponding author. Department of Surgery and Clinical Oncology (E2), Graduate School of Medicine, Osaka University, 2-2 Yamadaoka Suita, Osaka 565-0871, Japan. Tel.: +81-6-6879-3251; fax: +81-6-6879-3259.
    • ,
  • Mitsugu Sekimoto, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Shuji Takiguchi, M.D. Ph.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Masayoshi Yasui, M.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Katsuki Danno, M.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Yujiro Fujie, M.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Kotaro Kitani, M.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Yosuke Seki, M.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Taishi Hata, M.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Tatsushi Shingai, M.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Ichiro Takemasa, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Masakazu Ikenaga, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Osaka National Hospital, Osaka, Japan
    • ,
  • Hirofumi Yamamoto, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan
    • ,
  • Masayuki Ohue, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    • ,
  • Morito Monden, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Graduate School of Medicine, Osaka University, Suita, Japan

Received 12 September 2005 ,Revised 14 June 2006

References 

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  2. Rattner DW, Ellman L, Warshaw AL. Portal vein thrombosis after elective splenectomy (An underappreciated, potentially lethal syndrome). Arch Surg. 1993;128:565–569
  3. Pietrabissa A, Moretto C, Antonelli G, et al. Thrombosis in the portal venous system after elective laparoscopic splenectomy. Surg Endosc. 2004;18:1140–1143
  4. Winslow ER, Brunt LM, Drebin JA, et al. Portal vein thrombosis after splenectomy. Am J Surg. 2002;184:631–636
  5. Ikeda M, Sekimoto M, Takiguchi S, et al. High incidence of thrombosis of the portal venous system after laparoscopic splenectomy: a prospective study with contrast-enhanced CT scan. Ann Surg. 2005;241:208–216
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  9. van’t Riet M, Burger JWA, van Muiswinkel J, et al. Diagnosis and treatment of portal vein thrombosis following splenectomy. Br J Surg. 2000;87:1229–1233
  10. Fujita F, Lyass S, Otsuka K, et al. Portal vein thrombosis following splenectomy: identification of risk factors. Am Surg. 2003;69:951–956
  11. Miniati DN, Padidar AM, Kee ST, et al. Portal vein thrombosis after laparoscopic splenectomy: an ongoing clinical challenge. J Soc Laparoendosc Surg. 2005;9:335–338
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  14. Skarsgard E, Doski J, Jaksic T, et al. Thrombosis of the portal venous system after splenectomy for pediatric hematologic disease. J Pediatr Surg. 1993;28:1109–1112
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  17. Janssen HL, Wijnhoud A, Haagsma EB, et al. Extrahepatic portal vein thrombosis: aetiology and determinants of survival. Gut. 2001;49:720–724
  18. Condat B, Pessione F, Denninger MH, et al. Recent portal or mesenteric venous thrombosis: increased recognition and frequent recanalization on anticoagulant therapy. Hepatology. 2000;32:466–470
  19. Thompson EN, Sherlock S. The aetiology of portal vein thrombosis with particular reference to the role of infection and exchange transfusion. Q J Med. 1964;33:465–480
  20. Gordon DH, Schaffner D, Bennett JM, et al. Postsplenectomy thrombocytosis: its association with mesenteric, portal, and/or renal vein thrombosis in patients with myeloproliferative disorders. Arch Surg. 1978;113:713–715
  21. Boxer MA, Braun J, Ellman L. Thromboembolic risk of postsplenectomy thrombocytosis. Arch Surg. 1978;113:808–809
  22. Hanazaki K, Kajikawa S, Adachi W, et al. Portal vein thrombosis may be a fatal complication after synchronous splenectomy in patients with hepatocellular carcinoma and hypersplenism. J Am Coll Surg. 2000;191:341–342
  23. Amitrano L, Guardascione MA, Brancaccio V, et al. Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis. J Hepatol. 2004;40:736–741
  24. Rossi P, Passariello R, Simonetti G. Portal thrombosis: high incidence following splenectomy for portal hypertension. Gastrointest Radiol. 1976;1:225–227
  25. Freiman DG. The structure of thrombi. In:  Colman RW,  Hirsh J,  Marder VJ, et al. editor. Hemostasis and Thrombosis. 2nd ed.. Philadelphia: Lippincott; 1987;p. 1123–1135
  26. Poultsides GA, Lewis WC, Feld R, et al. Portal vein thrombosis after laparoscopic colectomy: thrombolytic therapy via the superior mesenteric vein. Am Surgeon. 2005;71:856–860

PII: S0002-9610(06)00690-8

doi: 10.1016/j.amjsurg.2006.06.036

The American Journal of Surgery
Volume 193, Issue 1 , Pages 21-25 , January 2007

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