The American Journal of Surgery
Volume 194, Issue 4 , Pages 444-449 , October 2007

Clinicopathologic features of papillary lesions on core needle biopsy of the breast predictive of malignancy

Presented at the 8th Annual Meeting of the American Society of Breast Surgeons, Phoenix, AZ, May 2–6, 2007

  • Nimmi Arora, M.D.

      Affiliations

    • Department of Surgery, New York Presbyterian Hospital-Cornell, 425 E. 61st St, New York, NY 10021, USA
    • ,
  • Chloe Hill, B.S.

      Affiliations

    • Department of Surgery, New York Presbyterian Hospital-Cornell, 425 E. 61st St, New York, NY 10021, USA
    • ,
  • Syed A. Hoda, M.D.

      Affiliations

    • Department of Pathology, New York Presbyterian Hospital-Cornell, 425 E. 61st St, New York, NY 10021, USA
    • ,
  • Ruth Rosenblatt, M.D.

      Affiliations

    • Department of Radiology, New York Presbyterian Hospital-Cornell, 425 E. 61st St, New York, NY 10021, USA
    • ,
  • Rodolfo Pigalarga, M.D.

      Affiliations

    • Department of Surgery, New York Presbyterian Hospital-Cornell, 425 E. 61st St, New York, NY 10021, USA
    • ,
  • Eleni A. Tousimis, M.D.

      Affiliations

    • Department of Surgery, New York Presbyterian Hospital-Cornell, 425 E. 61st St, New York, NY 10021, USA
    • Corresponding Author InformationCorresponding author. 425 E. 61st St, 10th Floor, New York, NY 10021. Tel.: +1-212-821-0850; fax: +1-212-821-0765.

Received 30 April 2007 ,Revised 2 July 2007

References 

  1. Fisher ER, Palekar AS, Redmond C, et al. Pathologic findings from the National Surgical Adjuvant Breast Project (protocol no. 4) (VI. Invasive papillary cancer). Am J Clin Pathol. 1980;73:313–322
  2. Rosen PP. Rosen’s breast pathology. 2nd ed.. Philadelphia: Lippincott Williams & Wilkins; 2001;
  3. Lam WW, Tang AP, Tse G, et al. Papillary carcinoma of the breast. Clin Imaging. 2005;29:396–400
  4. McCulloch GL, Evans AJ, Yeoman L, et al. Radiological features of papillary carcinoma of the breast. Clin Radiol. 1997;52:865–868
  5. Philpotts LE, Shaheen NA, Jain KS, et al. Uncommon high-risk lesions of the breast diagnosed at stereotactic core-needle biopsy: clinical importance. Radiology. 2000;216:831–837
  6. Lam WW, Chu WC, Tang AP, et al. Role of radiologic features in the management of papillary lesions of the breast. AJR Am J Roentgenol. 2006;186:1322–1327
  7. Rosen PP, Hoda SA. Breast pathology: diagnosis by needle core biopsy. 2nd ed.. Philadelphia: Lippincott Williams & Wilkins; 2006;
  8. Mercado CL, Hamele-Bena D, Oken SM, et al. Papillary lesions of the breast at percutaneous core-needle biopsy. Radiology. 2006;238:801–808
  9. Liberman L, Bracero N, Vuolo MA, et al. Percutaneous large-core biopsy of papillary breast lesions. AJR Am J Roentgenol. 1999;172:331–337
  10. Puglisi F, Zuiani C, Bazzocchi M, et al. Role of mammography, ultrasound and large core biopsy in the diagnostic evaluation of papillary breast lesions. Oncology. 2003;65:311–315
  11. Rosen EL, Bentley RC, Baker JA, et al. Imaging-guided core needle biopsy of papillary lesions of the breast. AJR Am J Roentgenol. 2002;179:1185–1192
  12. Bloodgood JC. Benign lesions of the female breast for which operation is not indicated. JAMA. 1922;78:859–863
  13. Gendler LS, Feldman SM, Balassanian R, et al. Association of breast cancer with papillary lesions identified at percutaneous image-guided breast biopsy. Am J Surg. 2004;188:365–370
  14. Valdes EK, Tartter PI, Genelus-Dominique E, et al. Significance of papillary lesions at percutaneous breast biopsy. Ann Surg Oncol. 2006;13:480–482
  15. Simsir A, Waisman J, Thorner K, et al. Mammary lesions diagnosed as “papillary” by aspiration biopsy: 70 cases with follow-up. Cancer. 2003;99:156–165
  16. Masood S, Loya A, Khalbuss W. Is core needle biopsy superior to fine-needle aspiration biopsy in the diagnosis of papillary breast lesions?. Diagn Cytopathol. 2003;28:329–334
  17. Jeffrey PB, Ljung BM. Benign and malignant papillary lesions of the breast (A cytomorphologic study). Am J Clin Pathol. 1994;101:500–507
  18. Ibarra JA. Papillary lesions of the breast. Breast J. 2006;12:237–251
  19. Page DL, Salhany KE, Jensen RA, et al. Subsequent breast carcinoma risk after biopsy with atypia in a breast papilloma. Cancer. 1996;78:258–266
  20. Renshaw AA, Derhagopian RP, Tizol-Blanco DM, et al. Papillomas and atypical papillomas in breast core needle biopsy specimens: risk of carcinoma in subsequent excision. Am J Clin Pathol. 2004;122:217–221
  21. Sydnor MK, Wilson JD, Hijaz TA, et al. Underestimation of the presence of breast carcinoma in papillary lesions initially diagnosed at core-needle biopsy. Radiology. 2007;242:58–62
  22. Nassar H, Qureshi H, Adsay VN, et al. Clinicopathologic analysis of solid papillary carcinoma of the breast and associated invasive carcinomas. Am J Surg Pathol. 2006;30:501–507
  23. Shah VI, Flowers CI, Douglas-Jones AG, et al. Immunohistochemistry increases the accuracy of diagnosis of benign papillary lesions in breast core needle biopsy specimens. Histopathology. 2006;48:683–691
  24. Lerwill MF. Current practical applications of diagnostic immunohistochemistry in breast pathology. Am J Surg Pathol. 2004;28:1076–1091
  25. Collins LC, Carlo VP, Hwang H, et al. Intracystic papillary carcinomas of the breast: a reevaluation using a panel of myoepithelial cell markers. Am J Surg Pathol. 2006;30:1002–1007
  26. Ichihara S, Fujimoto T, Hashimoto K, et al. Double immunostaining with p63 and high-molecular-weight cytokeratins distinguishes borderline papillary lesions of the breast. Pathol Int. 2007;57:126–132
  27. Mercado CL, Hamele-Bena D, Singer C, et al. Papillary lesions of the breast: evaluation with stereotactic directional vacuum-assisted biopsy. Radiology. 2001;22:650–655
  28. Ivan D, Selinko V, Sahin AA, et al. Accuracy of core needle biopsy diagnosis in assessing papillary breast lesions: histologic predictors of malignancy. Mod Pathol. 2004;17:165–171
  29. Carder PJ, Garvican J, Haigh I, et al. Needle core biopsy can reliably distinguish between benign and malignant papillary lesions of the breast. Histopathology. 2005;46:320–327
  30. Birusingh RJ, Merayo-Rodriguez JA, Escudero G, et al. Papillary neoplasms of the breast—a clinico-pathologic correlation between core needle biopsy and surgically resected specimens: a 5-year study at Danbury Hospital (2000-2005). [abstract] Arch Pathol Lab Med. 2006;130:1365

PII: S0002-9610(07)00556-9

doi: 10.1016/j.amjsurg.2007.07.004

The American Journal of Surgery
Volume 194, Issue 4 , Pages 444-449 , October 2007

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