The American Journal of Surgery
Volume 195, Issue 1 , Pages 34-39 , January 2008

The positive effect of adenoma weight and oxyphil cell content on preoperative localization with 99mTc-sestamibi scanning for primary hyperparathyroidism

  • Yeşim Erbil, M.D.

      Affiliations

    • Department of General Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • Corresponding Author InformationCorresponding author. Tel.: +011-902124142000; fax: +011-902124142000.
    • ,
  • Yersu Kapran, M.D.

      Affiliations

    • Department of Pathology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • ,
  • Halim İşsever, Ph.D.

      Affiliations

    • Department of Public Health, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • ,
  • Umut Barbaros, M.D.

      Affiliations

    • Department of General Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • ,
  • Işık Adalet, M.D.

      Affiliations

    • Nuclear Medicine, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • ,
  • Ferhunde Dizdaroğlu, M.D.

      Affiliations

    • Department of Pathology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • ,
  • Alp Bozbora, M.D.

      Affiliations

    • Department of General Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • ,
  • Selçuk Özarmağan, M.D.

      Affiliations

    • Department of General Surgery, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey
    • ,
  • Serdar Tezelman, M.D.

Received 27 October 2006 ,Revised 16 January 2007

References 

  1. Bilezikian JP, Silverberg SJ. Clinical spectrum of primary hyperparathyroidism. Rev Endocr Metab Disord. 2000;1:237–245
  2. Melton LJ. The epidemiology of primary hyperparathyroidism in North America. J Bone Miner Res. 2002;17:12–17
  3. Ogilvie JB, Clark OH. Parathyroid surgery: we still need traditional and selective approaches. J Endocrinol Invest J. 2005;28:566–569
  4. Ruda JM, Hollenbeak CS, Stack BC. A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003. Otolaryngol Head Neck Surg. 2005;132:359–372
  5. Sackett WR, Barraclough B, Reeve TS, et al. Worldwide trends in the surgical treatment of primary hyperparathyroidism in the era of minimally invasive parathyroidectomy. Arch Surg. 2002;137:1055–1059
  6. Costello D, Norman J. Minimally invasive radioguided parathyroidectomy. Surg Oncol Clin North Am. 1999;8:555–564
  7. Lowney JK, Weber B, Johnson S, et al. Minimal incision parathyroidectomy: cure, cosmesis, and cost. World J Surg. 2000;24:1442–1445
  8. Miura D, Wada N, Arıcı C, et al. Does intraoperative quick parathyroid hormone assay improve the results of parathyroidectomy?. World J Surg. 2002;26:926–930
  9. Siperstein A, Berber E, Mackey R, et al. Prospective evaluation of sestamibi scan, ultrasonography, and rapid PTH to predict the success of limited exploration for sporadic primary hyperparathyroidism. Surgery. 2004;136:872–880
  10. Miccoli P, Berti P. Minimally invasive parathyroid surgery. Best Pract Res Clin Endocrinol Metab. 2001;15:139–147
  11. Miccoli P, Berti P, Raffaelli M, et al. Comparison between minimally invasive video-assisted thyroidectomy and conventional thyroidectomy: a prospective randomized study. Surgery. 2001;130:1039–1043
  12. Coakley AJ, Kettle AG, Wells CP, et al. 99mTc-sestamibi: a new agent for parathyroid imaging. Nucl Med Commun. 1989;10:791–794
  13. Palestro CJ, Tomas MB, Tronco GG. Radionuclide imaging of the parathyroid glands. Semin Nucl Med. 2005;35:266–276
  14. Denham DW, Norman J. Cost-effectiveness of preoperative sestamibi scan for primary hyperparathyroidism is dependent solely upon the surgeon’s choice of operative procedure. J Am Coll Surg. 1998;186:293–305
  15. Lumachi F, Zucchetta P, Marzola MC, et al. Advantages of combined technetium-99m-sestamibi scintigraphy and high-resolution ultrasonography in parathyroid localization: comparative study in 91 patients with primary hyperparathyroidism. Eur J Endocrinol. 2000;143:755–760
  16. Allendorf J, Kim L, Chabot J, et al. The impact of sestamibi scanning on the outcome of parathyroid surgery. J Clin Endocrinol Metab. 2003;88:3015–3018
  17. Mihai R, Gleeson F, Buley ID, et al. Negative imaging studies for primary hyperparathyroidism are unavoidable: correlation of sestamibi and high-resolution ultrasound scanning with histological analysis in 150 patients. World J Surg. 2006;30:697–704
  18. Mehta NY, Ruda JM, Kapadia S, et al. Relationship of technetium Tc 99m sestamibi scans to histopathological features of hyperfunctioning parathyroid tissue. Arch Otolaryngol Head Neck Surg. 2005;131:493–498
  19. Yamaguchi S, Yachiku S, Hashimoto H, et al. Relation between technetium 99m methoxyisobutylisonitrile accumulation and multidrug resistance protein in the parathyroid glands. World J Surg. 2002;26:29–34
  20. Lumachi F, Marzola MC, Zucchetta P, et al. Hyperfunctioning parathyroid tumours in patients with thyroid nodules (Sensitivity and positive predictive value of high-resolution ultrasonography and 99mTc-sestamibi scintigraphy). Endocr Relat Cancer. 2003;10:419–423
  21. Krausz Y, Lebensart PD, Klein M, et al. Preoperative localization of parathyroid adenoma in patients with concomitant thyroid nodular disease. World J Surg. 2000;24:1573–1578
  22. Pinero A, Rodriguez JM, Ortiz S, et al. Relation of biochemical, cytologic, and morphologic parameters to the result of gammagraphy with technetium 99m sestamibi in primary hyperparathyroidism. Otolaryngol Head Neck Surg. 2000;122:851–855
  23. Ugur O, Bozkurt MF, Hamaloglu E, et al. Clinicopathologic and radiopharmacokinetic factors affecting gamma probe-guided parathyroidectomy. Arch Surg. 2004;139:1175–1179
  24. Biertho LD, Kim C, Wu HS, et al. Relationship between sestamibi uptake, parathyroid hormone assay, and nuclear morphology in primary hyperparathyroidism. J Am Coll Surg. 2004;199:229–233

PII: S0002-9610(07)00834-3

doi: 10.1016/j.amjsurg.2007.01.040

The American Journal of Surgery
Volume 195, Issue 1 , Pages 34-39 , January 2008

Article Tools

* Image Usage & Resolution