The American Journal of Surgery
Volume 195, Issue 2 , Pages 141-143 , February 2008

Postoperative antibiotic therapy for children with perforated appendicitis: long course of intravenous antibiotics versus early conversion to an oral regimen

Received 18 May 2007 ,Revised 15 October 2007

References 

  1. Muehlstedt SG, Pham TQ, Schmeling DJ. The management of pediatric appendicitis: a survey of North American pediatric surgeons. J Pediatr Surg. 2004;39:875–879
  2. Chen C, Botelho C, Cooper A, et al. Current practice patterns in the treatment of perforated appendicitis in children. J Am Coll Surg. 2003;196:212–221
  3. Rice HE, Brown RL, Gollin G, et al. Results of a pilot trial comparing prolonged intravenous antibiotics with sequential intravenous/oral antibiotics for children with perforated appendicitis. Arch Surg. 2001;136:1391–1395
  4. Schwartz MZ, Tapper D, Solenberger RI. Management of perforated appendicitis in children. Ann Surg. 1983;197:407–411
  5. Lund DP, Murphy EU. Management of perforated appendicitis in children: a decade of aggressive treatment. J Pediatr Surg. 1994;29:1130–1134
  6. Strovoff MC, Totten M, Glick PL. PIC lines save money and hasten discharge in the care of children with ruptured appendicitis. J Pediatr Surg. 1994;29:245–247
  7. Fishman SJ, Pelosi L, Klavon SL, et al. Perforated appendicitis: prospective outcome analysis for 150 children. J Pediatr Surg. 2000;35:923–926
  8. Banani SA, Talei A. Can oral metronidazole substitute parenteral drug therapy in acute appendicitis? (A new policy in the management of simple or complicated appendicitis with local peritonitis: a randomized controlled clinical trial). Am Surg. 1999;65:411–416
  9. Styrud J, Eriksson S, Granstrom L. Treatment of perforated appendicitis: an analysis of 362 patients during 8 years. Dig Surg. 1998;15:683–686
  10. Solomkin JS, Reinhart HH, Dellinger EP, et al. Results of a randomized trial comparing sequential intravenous/oral treatment with ciprofloxacin plus metronidazole to imipenem/cilastatin for intra-abdominal infections. Ann Surg. 1996;223:303–315
  11. Gollin G, Abarbanell A, Moores D. Oral antibiotics in the management of perforated appendicitis in children. Am Surg. 2002;68:1072–1074
  12. Cunha BA. Intravenous to oral antibiotic switch therapy. Drugs Today. 2001;37:311–319
  13. Branton LL, Lazo JS, Parker KL. Goodman and Gilman’s The Pharmacological Basis of Therapeutics. New York, NY: McGraw-Hill; 2006;

PII: S0002-9610(07)00882-3

doi: 10.1016/j.amjsurg.2007.10.002

The American Journal of Surgery
Volume 195, Issue 2 , Pages 141-143 , February 2008

Article Tools