The American Journal of Surgery
Volume 195, Issue 6 , Pages 775-781 , June 2008

Role of the width of the surgical margin in a hepatectomy for small hepatocellular carcinomas eligible for percutaneous local ablative therapy

Received 13 May 2007 ,Revised 12 June 2007

References 

  1. Takayama T, Makuuchi M, Hirohashi S, et al. Early hepatocellular carcinoma as an entity with a high rate of surgical cure. Hepatology. 1998;28:1241–1246
  2. Zhou XD, Tang ZY, Yang BH, et al. Experience of 1000 patients who underwent hepatectomy for small hepatocellular carcinoma. Cancer. 2001;91:1479–1489
  3. Ikai I, Arii S, Kojiro M, et al. Reevaluation of prognostic factors for survival after liver resection in patients with hepatocellular carcinoma in a Japanese nationwide survey. Cancer. 2004;101:796–802
  4. Shirabe K, Kanematsu T, Matsumata T, et al. Factors linked to early recurrences of small hepatocellular carcinoma after hepatectomy: univariate and multivariate analyses. Hepatology. 1991;14:802–805
  5. Kumada T, Nakano S, Takeda I, et al. Pattern of recurrence after initial treatment in patients with small hepatocellular carcinoma. Hepatology. 1997;25:87–92
  6. Okusaka T, Okada S, Ueno H, et al. Satellite lesions in patients with small hepatocellular carcinoma with reference to clinicopathologic features. Cancer. 2002;95:1931–1937
  7. Shi M, Zhang CQ, Zhang YQ, et al. Micrometastases of solitary hepatocellular carcinoma and appropriate resection margin. World J Surg. 2004;28:376–381
  8. Sasaki A, Kai S, Iwashita Y, et al. Microsatellite distribution and indication for locoregional therapy in small hepatocellular carcinoma. Cancer. 2005;103:299–306
  9. Nagasue N, Uchida M, Makino Y, et al. Incidence and factors associated with intrahepatic recurrence following resection of hepatocellular carcinoma. Gastroenterology. 1993;105:488–494
  10. Matsutani S, Sasaki Y, Imaoka S, et al. The prognostic significance of surgical margin in liver resection of patients with hepatocellular carcinoma. Arch Surg. 1994;129:1025–1030
  11. Chau GY, Lui WY, Tsay SH, et al. Prognostic significance of surgical margin in hepatocellular carcinoma resection: an analysis of 165 Child's A patients. J Surg Oncol. 1997;66:122–126
  12. Lise M, Bacchtti S, Da Pian P, et al. Prognostic factors affecting long term outcomes after liver resection for hepatocellular carcinoma: results in a series of 100 Italian patients. Cancer. 1998;82:1028–1036
  13. Shi M, Guo RP, Lin XJ, et al. Partial hepatectomy with wide versus narrow resection margin for solitary hepatocellular carcinoma a prospective randomized trial. Ann Surg. 2007;245:36–43
  14. Yoshida Y, Kanematsu T, Matsumata T, et al. Surgical margin and recurrence after resection for hepatocellular carcinoma in patients with cirrhosis: further evaluation of limited hepatic resection. Ann Surg. 1989;209:297–301
  15. Ochiai T, Takayama T, Inoue K, et al. Hepatic resection with and without surgical margins for hepatocellular carcinoma in patients with impaired liver function. Hepatogastroenterology. 1999;46:1885–1889
  16. Poon RT, Fan ST, Ng IO, et al. Significance of resection margin in hepatectomy for hepatocellular carcinoma: a critical reappraisal. Ann Surg. 2000;231:544–551
  17. Yamamoto J, Okada S, Shimada K, et al. Treatment strategy for small hepatocellular carcinoma: comparison of long term results after percutaneous ethanol injection therapy and surgical resection. Hepatology. 2001;34:707–713
  18. Teratani T, Yoshida H, Shiina S, et al. Radiofrequency ablation for hepatocellular carcinoma in so-called high-risk locations. Hepatology. 2006;43:1101–1108
  19. Huang GT, Lee PH, Tsang YK, et al. Percutaneous ethanol injection versus surgical resection for the treatment of small hepatocellular carcinoma a prospective study. Ann Surg. 2005;242:36–42
  20. Chen MS, Li JQ, Zheng Y, et al. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma. Ann Surg. 2006;243:321–328
  21. Liver Cancer Study Group of Japan. General Rules for the Clinical and Pathological Study of Primary Liver Cancer. 2nd Ed.. Tokyo: Kanehara; 2003;
  22. Huo TI, Wu JC, Hsia CY, et al. Hepatitis C virus infection is a risk factor for tumor recurrence after resection of small hepatocellular carcinomas. World J Surg. 2004;28:787–791
  23. Takenaka K, Adachi E, Nishizaki T, et al. Possible multicentric occurrence of hepatocellular carcinoma: a clinicopathological study. Hepatology. 1994;19:889–894
  24. Utsunomiya T, Shimada M, Taguchi KI, et al. Clinicopathologic features and postoperative prognosis of multicentric small hepatocellular carcinoma. J Am Coll Surg. 2000;190:331–335
  25. Hasegawa K, Kokudo N, Imamura H, et al. Prognostic impact of anatomic resection for hepatocellular carcinoma. Ann Surg. 2005;242:252–259

PII: S0002-9610(08)00186-4

doi: 10.1016/j.amjsurg.2007.06.033

The American Journal of Surgery
Volume 195, Issue 6 , Pages 775-781 , June 2008