The American Journal of Surgery
Volume 196, Issue 4 , Pages 470-476 , October 2008

Scientific Impact Recognition Award: Molecular breast imaging: A review of the Mayo Clinic experience

  • Carrie B. Hruska, M.D.

      Affiliations

    • Department of Nuclear Medicine, Mayo Clinic, Rochester, MN 55905, USA
  • ,
  • Judy C. Boughey, M.D.

      Affiliations

    • Department of Surgery, Mayo Clinic, Rochester, MN, USA
  • ,
  • Stephen W. Phillips, M.D.

      Affiliations

    • Department of Radiology, Mayo Clinic, Rochester, MN, USA
  • ,
  • Deborah J. Rhodes, M.D.

      Affiliations

    • Department of Internal Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN, USA
  • ,
  • Dietlind L. Wahner-Roedler, M.D.

      Affiliations

    • Department of Internal Medicine, Mayo Clinic, 200 First St. SW, Rochester, MN, USA
  • ,
  • Dana H. Whaley, M.D.

      Affiliations

    • Department of Radiology, Mayo Clinic, Rochester, MN, USA
  • ,
  • Amy C. Degnim, M.D.

      Affiliations

    • Department of Surgery, Mayo Clinic, Rochester, MN, USA
  • ,
  • Michael K. O'Connor, Ph.D.

      Affiliations

    • Department of Nuclear Medicine, Mayo Clinic, Rochester, MN 55905, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-507-284-4399; fax: +1-507-266-4461

Received 16 April 2008 ,Revised 12 June 2008

References 

  1. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer J Clin. 2008;58:71–96
  2. Kerlikowske K, Grady D, Rubin SM, et al. Efficacy of screening mammography: a meta-analysis. JAMA. 1995;273:149–154
  3. Tabar L, Vitak B, Chen HH, et al. Beyond randomized controlled trials: organized mammographic screening substantially reduces breast carcinoma mortality. Cancer. 2001;91:1724–1731
  4. Humphrey LL, Helfand M, Chan BKS, et al. Breast cancer screening: a summary of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med. 2002;137:347–360
  5. Carney PA, Miglioretti DL, Yankaskas BC, et al. Individual and combined effects of age, breast density, and hormone replacement therapy use on the accuracy of screening mammography. Ann Intern Med. 2003;138:168–175
  6. Kolb TM, Lichy J, Newhouse JH. Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations. Radiology. 2002;225:165–175
  7. Leconte I, Feger C, Galant C, et al. Mammography and subsequent whole-breast sonography of nonpalpable breast cancers: the importance of radiologic breast density. AJR Am J Roentgenol. 2003;180:1675–1679
  8. Khalkhali I, Baurn JK, Villanueva-Meyer J, et al. 99mTc-sestamibi breast imaging for the examination of patients with dense and fatty breasts: multicenter study. Radiology. 2002;222:149–155
  9. Khalkhali I, Vargas HI. The role of nuclear medicine in breast cancer detection: functional breast imaging. Radiol Clin North Am. 2001;39:1053–1068
  10. Khalkhali I, Villanueva-Meyer J, Edell SL, et al. Diagnostic accuracy of 99mTc-sestamibi breast imaging: multicenter trial results. J Nucl Med. 2000;41:1973–1979
  11. Majewski S, Kieper D, Curran E, et al. Optimization of dedicated scintimammography procedure using detector prototypes and compressible phantoms. IEEE Trans Nucl Sci. 2001;48:822–829
  12. McElroy DP, Hoffman EJ, MacDonald L, et al. Evaluation of breast tumor detectability with two dedicated, compact scintillation cameras. IEEE Trans Nucl Sci. 2002;49:794–802
  13. Pani R, Soluri A, Scafe R, et al. Multi-PSPMT scintillation camera. IEEE Trans Nucl Sci. 1999;46:702–708
  14. Gruber GJ, Moses WW, Derenzo SE, et al. A discrete scintillation camera module using silicon photodiode readout of CsI(Tl) crystals for breast cancer imaging. IEEE Trans Nucl Sci. 1998;45:1063–1068
  15. Patt BE, Iwanczyk JS, Rossington Tull C, et al. High resolution CsI(Tl)/Si-PIN detector development for breast imaging. IEEE Trans Nucl Sci. 1998;45:2126–2131
  16. Kim JH, Choi Y, Joo KS, et al. Development of a miniature scintillation camera using an NaI(Tl) scintillator and PSPMT for scintimammography. Phys Med Biol. 2000;45:3481–3488
  17. Mueller B, O'Connor MK, Blevis I, et al. Evaluation of a small cadmium zinc telluride detector for scintimammography. J Nucl Med. 2003;44:602–609
  18. Hruska CB, O'Connor MK, Collins DA. Comparison of small field of view gamma camera systems for scintimammography. Nucl Med Commun. 2005;26:441–445
  19. Rhodes DJ, O'Connor MK, Phillips SW, et al. Molecular breast imaging: a new technique using technetium Tc 99m scintimammography to detect small tumors of the breast. Mayo Clin Proc. 2005;80:24–30
  20. Hruska CB, O'Connor MK. Effect of collimator selection on tumor detection for dedicated nuclear breast imaging systems. IEEE Trans Nuc Sci. 2006;53:2680–2689
  21. O'Connor MK, Phillips SW, Hruska CB, et al. Molecular breast imaging: advantages and limitations of a scintimammographic technique in patients with small breast tumors. Breast J. 2007;13:3–11
  22. American College of Radiology. Illustrated Breast Imaging Reporting and Data System (BI-RADS). 4th ed.. Reston, VA: American College of Radiology; 2003;
  23. Spanu A, Cottu P, Manca A, et al. Scintimammography with dedicated breast camera in unifocal and multifocal/multicentric primary breast cancer detection: a comparative study with SPECT. Int J Oncol. 2007;31:369–377
  24. Scopinaro F, Pani R, de Vincentis G, et al. High resolution scintimammography improves the accuracy of Tc-99m methoxyisobutylisonitrile scintimammography: use of a new dedicated gamma camera. Eur J Nucl Med. 1999;26:1279–1288
  25. Brem RF, Schoonjans JM, Kieper DA, et al. High-resolution scintimammography: a pilot study. J Nucl Med. 2002;43:909–915
  26. Coover LR, Caravaglia G, Kuhn P. Scintimammography with dedicated breast camera detects and localizes occult carcinoma. J Nucl Med. 2004;45:553–558
  27. Brem RF, Rapelyea JA, Zisman G, et al. Occult breast cancer: Scintimammography with high-resolution breast-specific gamma camera in women at high risk for breast cancer. Radiology. 2005;237:274–280
  28. Dibble SL, Israel J, Nussey B, et al. Mammography with breast cushions. Womens Health Issues. 2005;15:55–63
  29. Kuhl C, Kuhn W, Braun M, et al. Pre-operative staging of breast cancer with breast MRI: one step forward, two steps back?. Breast. 2007;16(Suppl):S34–S44
  30. Ciarmiello A, Del Vecchio S, Silvestro P, et al. Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer. J Clin Oncol. 1998;16:1677–1683
  31. Vecchio SD, Ciarmiello A, Potena MI, et al. In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients. Eur J Nucl Med. 1997;24:150–159
  32. Travaini LL, Baio SM, Cremonesi M, et al. Neoadjuvant therapy in locally advanced breast cancer: 99mTc-MIBI mammoscintigraphy is not a reliable technique to predict therapy response. Breast. 2007;16:262–270

PII: S0002-9610(08)00454-6

doi: 10.1016/j.amjsurg.2008.06.005

The American Journal of Surgery
Volume 196, Issue 4 , Pages 470-476 , October 2008