The American Journal of Surgery
Volume 196, Issue 4 , Pages 519-522 , October 2008

Impact of neoadjuvant chemotherapy on rate of tissue expander/implant loss and progression to successful breast reconstruction following mastectomy

  • Jonathan Mitchem, M.D.

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA
    • ,
  • Dave Herrmann

      Affiliations

    • B.S. Rush University Medical School, Chicago, Ill, USA
    • ,
  • Julie A. Margenthaler, M.D.

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA
    • Alvin J. Siteman Cancer Center, St. Louis MO, USA
    • ,
  • Rebecca L. Aft, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA
    • Alvin J. Siteman Cancer Center, St. Louis MO, USA
    • John Cochran Veterans Hospital, St. Louis, MO, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-314-747-0063; fax: +1-314-454-5509

Received 17 April 2008 ,Revised 27 May 2008

References 

  1. Eberlein TJ, Crespo LD, Smith BL, et al. Prospective evaluation of immediate reconstruction after mastectomy. Ann Surg. 1993;218:29–36
  2. Malata CM, McIntosh SA, Parushotham AD. Immediate breast reconstruction after mastectomy for cancer. Br J Surg. 2000;87:1455–1472
  3. Wright JL, Cordeiro PG, Ben-Porat L, et al. Mastectomy with immediate expander-implant reconstruction, adjuvant chemotherapy, and radiation for stage II-III breast cancer: treatment intervals and clinical outcome. Int J Radiat Oncol Biol Phys. 2008;70:43–50
  4. Kronowitz SJ. Immediate versus delayed reconstruction. Clin Plast Surg. 2007;34:39–50
  5. Furey PC, Macgillivray DC, Castiglione CL, et al. Wound complications in patients receiving adjuvant chemotherapy after mastectomy and immediate breast reconstruction for breast cancer. J Surg Oncol. 1994;55:194–197
  6. Pinsolle V, Grinfeder C, Mathoulin-Pelissier S, et al. Complications analysis of 266 immediate breast reconstructions. J Plastic Recon Aesth Surg. 2006;59:1017–1024
  7. Cordeiro PG, Pusic AL, Disa JJ, et al. Irradiation after immediate tissue expander/implant breast reconstruction: outcomes, complications, aesthetic results, and satisfaction among 156 patients. Plast Reconstruct Surg. 2004;113:877–881
  8. Krueger EA, Wilkins EG, Strawderman M, et al. Complications and patient satisfaction following expander/implant breast reconstruction with and without radiotherapy. Int J Radiat Oncol Biol Phys. 2001;49:713–721
  9. Gouy S, Rouzier R, Missana MC, et al. Immediate reconstruction after neoadjuvant chemotherapy: effect on adjuvant treatment starting and survival. Ann Surg Oncol. 2005;12:161–166

 Supported in part by grants from Novartis Pharmaceutical Corp. East Hanover, NJ and Pfizer, Inc., Peapack, NJ.

PII: S0002-9610(08)00476-5

doi: 10.1016/j.amjsurg.2008.06.016

The American Journal of Surgery
Volume 196, Issue 4 , Pages 519-522 , October 2008

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