The American Journal of Surgery
Volume 198, Issue 1 , Pages 46-50 , July 2009

Accurate axillary lymph node dissection is feasible after neoadjuvant chemotherapy

  • Marieke E. Straver, M.D.

      Affiliations

    • Department of Surgery, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +0031-20-5122999; fax: +0031-20-5122554
    • ,
  • Emiel J.T. Rutgers, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    • ,
  • Hester S.A. Oldenburg, M.D., Ph.D.

      Affiliations

    • Department of Surgery, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    • ,
  • Jelle Wesseling, M.D., Ph.D.

      Affiliations

    • Department of Pathology, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    • ,
  • Sabine C. Linn, M.D., Ph.D.

      Affiliations

    • Department of Medical Oncology, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    • ,
  • Nicola S. Russell, M.D., Ph.D.

      Affiliations

    • Department of Radiation Oncology, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    • ,
  • Marie-Jeanne T.F.D. Vrancken Peeters, M.D., Ph.D

      Affiliations

    • Department of Surgery, Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands

Received 18 January 2008 ,Revised 19 May 2008

References 

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  3. Krag DN, Single RM. Breast cancer survival according to number of nodes removed. Ann Surg Oncol. 2003;10:1152–1159
  4. Truong PT, Berthelet E, Lee J, et al. The prognostic significance of the percentage of positive/dissected axillary lymph nodes in breast cancer recurrence and survival in patients with one to three positive axillary lymph nodes. Cancer. 2005;103:2006–2014
  5. Kiricuta CI, Tausch J. A mathematical model of axillary lymph node involvement based on 1446 complete axillary dissections in patients with breast carcinoma. Cancer. 1992;69:2496–2501
  6. Axelsson CK, Mouridsen HT, During M, et al. Axillary staging during surgery for breast cancer. Br J Surg. 2007;94:304–309
  7. Danforth DN, Findlay PA, McDonald HD, et al. Complete axillary lymph node dissection for stage I-II carcinoma of the breast. J Clin Oncol. 1986;4:655–662
  8. Fisher B, Jeong JH, Anderson S, et al. Twenty-five-year follow-up of a randomized trial comparing radical mastectomy, total mastectomy, and total mastectomy followed by irradiation. N Engl J Med. 2002;347:567–575
  9. Orr RK. The impact of prophylactic axillary node dissection on breast cancer survival—a Bayesian meta-analysis. Ann Surg Oncol. 1999;6:109–116
  10. Baslaim MM, Al Malik OA, Al Sobhi SS, et al. Decreased axillary lymph node retrieval in patients after neoadjuvant chemotherapy. Am J Surg. 2002;184:299–301
  11. Neuman H, Carey LA, Ollila DW, et al. Axillary lymph node count is lower after neoadjuvant chemotherapy. Am J Surg. 2006;191:827–829
  12. van Tienhoven G, Borger JH, Passchier DH, et al. The prognostic significance of the axillary apex biopsy in clinically operable breast cancer. Eur J Cancer. 1995;31A:1965–1968
  13. Patel NA, Piper G, Patel JA, et al. Accurate axillary nodal staging can be achieved after neoadjuvant therapy for locally advanced breast cancer. Am Surg. 2004;70:696–699
  14. Kuerer HM, Sahin AA, Hunt KK, et al. Incidence and impact of documented eradication of breast cancer axillary lymph node metastases before surgery in patients treated with neoadjuvant chemotherapy. Ann Surg. 1999;230:72–78
  15. Rouzier R, Extra JM, Klijanienko J, et al. Incidence and prognostic significance of complete axillary downstaging after primary chemotherapy in breast cancer patients with T1 to T3 tumors and cytologically proven axillary metastatic lymph nodes. J Clin Oncol. 2002;20:1304–1310

PII: S0002-9610(08)00555-2

doi: 10.1016/j.amjsurg.2008.05.006

The American Journal of Surgery
Volume 198, Issue 1 , Pages 46-50 , July 2009

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