Outcomes of hepatic resection for hepatolithiasis

Uenishi, Takahiro; Hamba, Hiroyuki; Takemura, Shigekazu; Oba, Kazuki; Ogawa, Masao; Yamamoto, Takatsugu; Tanaka, Shogo; Kubo, Shoji

doi:10.1016/j.amjsurg.2008.08.020

« Previous Next »The American Journal of Surgery
Volume 198, Issue 2 , Pages 199-202, August 2009

Outcomes of hepatic resection for hepatolithiasis

Takahiro Uenishi, M.D.
- Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545–8585, Japan
- Corresponding author. Tel.: +81-6-6645-3841; fax: +81-6-6646-6057
Hiroyuki Hamba, M.D.
- Department of Surgery, Kita City Hospital, Osaka, Japan
Shigekazu Takemura, M.D.
- Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545–8585, Japan
Kazuki Oba, M.D.
- Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545–8585, Japan
Masao Ogawa, M.D.
- Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545–8585, Japan
Takatsugu Yamamoto, M.D.
- Department of Surgery, Ishikiriseiki Hospital, Higashi-Osaka, Japan
Shogo Tanaka, M.D.
- Department of Surgery, Ishikiriseiki Hospital, Higashi-Osaka, Japan
Shoji Kubo, M.D.
- Department of Hepato-Biliary-Pancreatic Surgery, Osaka City University, Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545–8585, Japan

Received 1 July 2008; received in revised form 2 August 2008 published online 02 March 2009.

Abstract

Background

Hepatic resection is main approach to treatment of hepatolithiasis, but the long-term follow-up results of hepatic resection for hepatolithiasis are rarely reported.

Methods

A retrospective study was conducted of 87 patients with hepatolithiasis who underwent hepatic resection.

Results

The final stone clearance rates were 95%. There was a significant difference in the incidence of recurrent stones between patients with and without remaining biliary strictures. On multivariate analysis, the presence of residual or recurrent stones was an independent risk factor associated with recurrent cholangitis. The 10-year overall survival rate was 80.3%. On multivariate analysis, the development of cholangiocarcinoma was an independent predictor of survival in patients who underwent hepatic resection for hepatolithiasis.

Conclusions

The long-term outcomes after hepatic resection were satisfactory in patients whose intrahepatic stones and strictures were completely removed. Cholangiocarcinoma associated with hepatolithiasis was an independent prognostic factor in patients with hepatolithiasis who underwent hepatic resection.

Keywords: Intrahepatic stones, Hepatectomy, Postoperative outcomes, Cholangiocarcinoma