The American Journal of Surgery
Volume 198, Issue 3 , Pages 359-367 , September 2009

Deep and organ/space infections in patients undergoing elective colorectal surgery: incidence and impact on hospital length of stay and costs

  • Kathryn J. Eagye, M.P.H.

      Affiliations

    • Center for AntiInfective Research and Development, Hartford Hospital, Hartford, CT, United States
    • ,
  • David P. Nicolau, Pharm.D., F.C.C.P., F.I.D.S.A.

      Affiliations

    • Center for AntiInfective Research and Development, Hartford Hospital, Hartford, CT, United States
    • Division of Infectious Diseases, Hartford Hospital, Hartford, CT, United States
    • Corresponding Author InformationCorresponding author. Tel.: +01-860-545-3941; fax: +01-860-545-3992

Received 4 March 2008 ,Revised 3 November 2008

References 

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  2. Kirkland KB, Briggs JP, Trivette SL, et al. The impact of surgical-site infections in the 1990s: attributable mortality, excess length of hospitalization, and extra costs. Infect Control Hosp Epidemiol. 1999;20:725–730
  3. Urban JA. Cost analysis of surgical site infections. Surg Infect (Larchmt). 2006;7(suppl 1):S19–S22
  4. Eagye KJ, Kim A, Laohavaleeson S, et al. Surgical site infections: does inadequate antibiotic therapy affect patient outcomes? J Infect (in press).
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  7. Song F, Glenny AM. Antimicrobial prophylaxis in colorectal surgery: a systematic review of randomized controlled trials. Br J Surg. 1998;85:1232–1241
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  10. Bratzler DW, Hunt DR. The surgical infection prevention and surgical care improvement projects: national initiatives to improve outcomes for patients having surgery. Clin Infect Dis. 2006;43:322–330
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  12. Bratzler DW, Houck PM. Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project. Clin Infect Dis. 2004;38:1706–1715
  13. Itani KM, Wilson SE, Awad SS, et al. Ertapenem versus cefotetan prophylaxis in elective colorectal surgery. N Engl J Med. 2006;355:2640–2651
  14. Schmelzer TM, Mostafa G, Lincourt AE, et al. Factors affecting length of stay following colonic resection. J Surg Res. 2007;
  15. Konishi T, Watanabe T, Kishimoto J, et al. Elective colon and rectal surgery differ in risk factors for wound infection: results of prospective surveillance. Ann Surg. 2006;244:758–763
  16. Garibaldi RA, Cushing D, Lerer T. Risk factors for postoperative infection. Am J Med. 1991;91:158S–163S
  17. Fujita S, Saito N, Yamada T, et al. Randomized, multicenter trial of antibiotic prophylaxis in elective colorectal surgery: single dose vs 3 doses of a second-generation cephalosporin without metronidazole and oral antibiotics. Arch Surg. 2007;142:657–661
  18. Guinier D, Mantion GA, Alves A, et al. Risk factors of unplanned readmission after colorectal surgery: a prospective, multicenter study. Dis Colon Rectum. 2007;50:1316–1323
  19. Boni L, Benevento A, Rovera F, et al. Infective complications in laparoscopic surgery. Surg Infect (Larchmt). 2006;7(suppl 2):S109–S111
  20. Hinojosa MW, Murrell ZA, Konyalian VR, et al. Comparison of laparoscopic vs open sigmoid colectomy for benign and malignant disease at academic medical centers. J Gastrointest Surg. 2007;11:1423–1430

PII: S0002-9610(09)00049-X

doi: 10.1016/j.amjsurg.2008.11.030

The American Journal of Surgery
Volume 198, Issue 3 , Pages 359-367 , September 2009

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