The American Journal of Surgery
Volume 197, Issue 5 , Pages 576-580 , May 2009

A highly porous silica and chitosan-based hemostatic dressing is superior in controlling hemorrhage in a severe groin injury model in swine

Received 7 November 2008 ,Revised 16 December 2008

References 

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  3. Kelly JF, Ritenour AE, McLaughlin DF, et al. Injury severity and causes of death from Operation Iraqi Freedom and Operation Enduring Freedom: 2003–2004 versus 2006. J Trauma. 2008;64:S21–S27
  4. Acheson EM, Kheirabadi BS, Deguzman R, et al. Comparison of hemorrhage control agents applied to lethal extremity arterial hemorrhages in swine. J Trauma. 2005;59:865
  5. Alam HB, Chen Z, Jaskille A, et al. Application of a zeolite hemostatic agent achieves 100% survival in a lethal model of complex groin injury in swine. J Trauma. 2004;56:974–983
  6. Kozen BG, Kircher SJ, Henao J, et al. An alternative hemostatic dressing: comparison of CELOX, HemCon, and QuikClot. Acad Emerg Med. 2008;15:74–81
  7. Carraway JW, Kent D, Young K, et al. Comparison of a new mineral based hemostatic agent to a commercially available granular zeolite agent for hemostasis in a swine model of lethal extremity arterial hemorrhage. Resuscitation. 2008;78:230–235
  8. Arnaud F, Tomori T, Carr W, et al. Exothermic reaction in zeolite hemostatic dressings: QuikClot ACS and ACS. Ann Biomed Eng. 2008;36:1708–1713
  9. Arnaud F, Tomori T, Saito R, et al. Comparative efficacy of granular and bagged formulations of the hemostatic agent QuikClot. J Trauma. 2007;63:775–782
  10. Ward KR, Tiba MH, Holbert WH, et al. Comparison of a new hemostatic agent to current combat hemostatic agents in a swine model of lethal extremity arterial hemorrhage. J Trauma. 2007;63:276–284
  11. Kheirabadi BS, Acheson EM, Deguzman R, et al. The potential utility of fibrin sealant dressing in repair of vascular injury in swine. J Trauma. 2007;62:94–103
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  14. Englehart MS, Cho SD, Tieu BH, et al. A novel highly porous silica and chitosan-based hemostatic dressing is superior to HemCon and gauze sponges. J Trauma. 2008;65:884–892
  15. Wedmore I, McManus JG, Pusateri AE, et al. A special report on the chitosan-based hemostatic dressing: experience in current combat operations. J Trauma. 2006;60:655–658
  16. Ahuja N, Ostomel TA, Rhee P, et al. Testing of modified zeolite hemostatic dressings in a large animal model of lethal groin injury. J Trauma. 2006;61:1312–1320
  17. Brown MA, Daya MR, Worley JA. Experience with chitosan dressings in a civilian EMS system. J Emerg Med. 2007;Epub ahead of print—doi:10.1016/j.jemermed.2007.05.043
  18. Malmquist JP, Clemens SC, Oien HJ, et al. Hemostasis of oral surgery wounds with the HemCon dental dressing. J Oral Maxillofac Surg. 2008;66:1177–1183

 No member of the study team has any financial or vested interest in OreMedix or its parent company ENTEK and there are no conflicts of interest.

PII: S0002-9610(09)00072-5

doi: 10.1016/j.amjsurg.2008.12.011

The American Journal of Surgery
Volume 197, Issue 5 , Pages 576-580 , May 2009

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