The American Journal of Surgery
Volume 197, Issue 5 , Pages 648-654 , May 2009

Intact parathyroid hormone measurement 1 hour after thyroid surgery identifies individuals at high risk for the development of symptomatic hypocalcemia

  • Jean Paul Lim, M.D.

      Affiliations

    • Department of Medicine, University of British Columbia, Vancouver, BC, Canada
    • ,
  • Robert Irvine, M.D., F.R.C.S.(C.)

      Affiliations

    • Department of Surgery, St. Paul's Hospital, University of British Columbia, C303-1081 Burrard Street, Vancouver, BC, Canada V6Z-1Y6
    • ,
  • Samuel Bugis, M.D., F.R.C.S.(C.)

      Affiliations

    • Department of Surgery, St. Paul's Hospital, University of British Columbia, C303-1081 Burrard Street, Vancouver, BC, Canada V6Z-1Y6
    • ,
  • Daniel Holmes, M.D., F.R.C.P.C.

      Affiliations

    • Department of Pathology and Laboratory Medicine, St. Paul's Hospital and University of British Columbia, Vancouver, BC, Canada
    • ,
  • Sam M. Wiseman, M.D., F.R.C.S.(C.)

      Affiliations

    • Department of Surgery, St. Paul's Hospital, University of British Columbia, C303-1081 Burrard Street, Vancouver, BC, Canada V6Z-1Y6
    • Corresponding Author InformationCorresponding author. Tel.: +1-604-806-9108; fax: +1-604-806-9957

Received 6 November 2008 ,Revised 17 December 2008

References 

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  2. Wiseman SM, Tomljanovich PI, Rigual NR. Thyroid lobectomy: operative anatomy, technique, and morbidity. Oper Tech Otolaryngol. 2004;15:210–219
  3. Noordzij JP, Lee SL, Bernet VJ, et al. Early prediction of hypocalcemia after thyroidectomy using parathyroid hormone: an analysis of pooled individual patient data from nine observational studies. J Am Coll Surg. 2007;205:748–754
  4. Orr RK, Patel VS, Rousseau CJ. 100 Consecutive thyroidectomies performed by a single surgeon in an upstate South Carolina Teaching Hospital: an outcome analysis. J S C Med Assoc. 2006;102:337–340
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  10. Higgins KM, Mandell DL, Govindaraj S, et al. The role of intraoperative rapid parathyroid hormone measurement for predicting thyroidectomy-related hypocalcemia. Arch Otolaryngol Head Neck Surg. 2004;130:63–67
  11. Lam A, Kerr P. Parathyroid hormone: an early predictor of Postthyroidectomy hypocalcemia. Laryngoscope. 2003;113:2196–2200
  12. Payne RJ, Tewfik MA, Hier MP, et al. Benefits resulting from 1-and 6-hour parathyroid hormone and calcium levels after thyroidectomy. Otolaryngol Head Neck Surg. 2005;133:386–390
  13. Payne RJ, Hier MP, Tamillia M, et al. Postoperative parathyroid hormone level as a predictor of post-thyroidectomy hypocalcmia. J Otolaryngol. 2003;32:362–369
  14. Quiros RM, Pesce CE, Wihelm SM. Intraoperative parathyroid hormone levels in thyroid surgery are predictive of postoperative hypoparathyroidism and need for vitamin D supplementation. Am J Surg. 2005;189:306–309
  15. Shoman N, Melck A, Holmes D, et al. Utility of intraoperative parathyroid hormone measurement in predicting postparathyroidectomy hypocalcemia. J Otolaryngol Head Neck Surg. 2008;37:16–22
  16. Lombardi CP, Raffaelli M, Princi P, et al. Early prediction of postthyroidectomy hypocalcemia by one single iPTH measurement. Sugery. 2004;136:1236–1241
  17. Vescan A, Witterick I, Freeman J. Parathyroid hormone as a predictor of hypocalcemia after thyroidectomy. Laryngoscope. 2005;115:105–108
  18. Lombardi CP, Raffaelli M, Princi P, et al. Parathyroid hormone levels 4 hours after surgery do not accurately predict post-thyroidectomy hypocalcemia. Surgery. 2006;140:1016–1023
  19. Grodski S, Lundgren CI, Sidhu S, et al. Post-operative PTH measurement facilitates day 1 discharge after total thyroidectomy. Clin Endocrinol. 2008;70:322–325

 SMW is a Michael Smith Foundation for Health Research (MSFHR) Scholar, and this work was supported by the MSFHR and the University of British Columbia Department of Surgery.

PII: S0002-9610(09)00073-7

doi: 10.1016/j.amjsurg.2008.12.012

The American Journal of Surgery
Volume 197, Issue 5 , Pages 648-654 , May 2009

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