The American Journal of Surgery
Volume 199, Issue 1 , Pages 14-20 , January 2010

Modern wound care for the poor: a randomized clinical trial comparing the vacuum system with conventional saline-soaked gauze dressings

  • Daniel Perez, M.D.

      Affiliations

    • Department of General Surgery, Hôpital Albert Schweitzer, Deschapelles, Haiti
    • Department of General Surgery, General Hospital Zurich-Triemli, Birmensdorfstrasse 497, 8063 Switzerland
    • Corresponding Author InformationCorresponding author: Tel.: +41-44-4661049; fax: +41-44-466-3606
    • ,
  • Matthias Bramkamp, M.D.

      Affiliations

    • Department of Internal Medicine, University Hospital of Zurich, Switzerland
    • ,
  • Chauvet Exe, M.D.

      Affiliations

    • Department of General Surgery, Hôpital Albert Schweitzer, Deschapelles, Haiti
    • ,
  • Christian von Ruden, M.D.

      Affiliations

    • Department of Trauma Surgery, University Hospital of Zurich, Switzerland
    • ,
  • Anna Ziegler, M.D.

      Affiliations

    • Department of General Surgery, Hôpital Albert Schweitzer, Deschapelles, Haiti
    • Department of Paediatrics, University Children's Hospital of Zurich, Switzerland

Received 21 June 2008 ,Revised 17 December 2008

References 

  1. Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997;38:563–576
  2. Argenta LC, Morykwas MJ, Marks MW, et al. Vacuum-assisted closure: state of clinic art. Plast Reconstr Surg. 2006;117(Suppl):127S–142S
  3. Venturi ML, Attinger CE, Mesbahi AN, et al. Mechanisms and clinical applications of the vacuum-assisted closure (VAC) device: a review. Am J Clin Dermatol. 2005;6:185–194
  4. Perez D, Wildi S, Clavien PA. The use of an abdominal vacuum-dressing system in the management of abdominal wound complications. Adv Surg. 2007;41:121–131
  5. Morykwas MJ, Simpson J, Punger K, et al. Vacuum-assisted closure: state of basic research and physiologic foundation. Plast Reconstr Surg. 2006;117(Suppl):121S–126S
  6. Perez D, Wildi S, Demartines N, et al. Prospective evaluation of vacuum-assisted closure in abdominal compartment syndrome and severe abdominal sepsis. J Am Coll Surg. 2007;205:586–592
  7. Banwell PE, Musgrave M. Topical negative pressure therapy: mechanisms and indications. Int Wound J. 2004;1:95–106
  8. Fu X, Wang Z, Sheng Z. Advances in wound healing research in China: from antiquity to the present. Wound Repair Regen. 2001;9:2–10
  9. Yearbook of the United Nations 2004: A More Secure World—Our Shared Responsibility. United Nations Publications, Department of Public Information; 2006;
  10. Jensen JL, Seeley J, Gillin B. Diabetic foot ulcerations (A controlled, randomized comparison of two moist wound healing protocols: Carrasyn hydrogel wound dressing and wet-to-moist saline gauze). Adv Wound Care. 1998;11(Suppl):1–4
  11. Braakenburg A, Obdeijn MC, Feitz R, et al. The clinical efficacy and cost effectiveness of the vacuum-assisted closure technique in the management of acute and chronic wounds: a randomized controlled trial. Plast Reconstr Surg. 2006;118:390–397
  12. Moues CM, Vos MC, van den Bemd GJ, et al. Bacterial load in relation to vacuum-assisted closure wound therapy: a prospective randomized trial. Wound Repair Regen. 2004;12:11–17
  13. Vuerstaek JD, Vainas T, Wuite J, et al. State-of-the-art treatment of chronic leg ulcers: A randomized controlled trial comparing vacuum-assisted closure (V.A.C.) with modern wound dressings. J Vasc Surg. 2006;44:1029–1037
  14. Cooper D. Human wound assessment: status report and implications for the clinician. AACN Clin Issues. 1990;1:553–565
  15. Sterling C. Methods of wound assessment documentation: a study. Nurs Stand. 1996;11:38–41
  16. Schmidt WD, Liebold K, Fassler D, et al. Contact-free spectroscopy of leg ulcers: principle, technique, and calculation of spectroscopic wound scores. J Invest Dermatol. 2001;116:531–535
  17. Bowler PG. Wound pathophysiology, infection and therapeutic options. Ann Med. 2002;34:419–427
  18. Mendonca DA, Papini R, Price PE. Negative-pressure wound therapy: a snapshot of the evidence. Int Wound J. 2006;3:261–271
  19. Johnson TM, Lowe L, Brown MD, et al. Histology and Physiology of tissue expansion. J Dermatol Surg Oncol. 1993;19:1074–1078
  20. Philbeck TE, Whittington KT, Millsap MH, et al. The clinical and cost effectiveness of externally applied negative pressure wound therapy in the treatment of wounds in home healthcare Medicare patients. Ostomy Wound Manage. 1999;45:41–50
  21. Wilson JR, Mills JG, Prather ID, et al. A toxicity index of skin and wound cleansers used on in vitro fibroblasts and keratinocytes. Adv Skin Wound Care. 2005;18:373–378
  22. Fumal I, Braham C, Paquet P, et al. The beneficial toxicity paradox of antimicrobials in leg ulcer healing impaired by a polymicrobial flora: a proof-of-concept study. Dermatology. 2002;204(Suppl 1):70–74
  23. Balin AK, Pratt L. Dilute povidone-iodine solutions inhibit human skin fibroblast growth. Dermatol Surg. 2002;28:210–214

PII: S0002-9610(09)00111-1

doi: 10.1016/j.amjsurg.2008.12.029

The American Journal of Surgery
Volume 199, Issue 1 , Pages 14-20 , January 2010

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