The American Journal of Surgery
Volume 199, Issue 2 , Pages 204-209 , February 2010

Six-year experience: long-term disease control outcomes for partial breast irradiation using MammoSite balloon brachytherapy

Presented at the 31st Annual San Antonio Breast Cancer Symposium, December 10–14, 2008, San Antonio, TX.

  • Jennifer L. Harper, M.D.

      Affiliations

    • Department of Radiation Oncology, Medical University of South Carolina, Hollings Cancer Center, 169 Ashley Ave. MSC 318 Charleston, SC 29425, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-843-792-3271; fax: +1-843-792-5472.
    • ,
  • John M. Watkins, M.D.

      Affiliations

    • Department of Radiation Oncology, Medical University of South Carolina, Hollings Cancer Center, 169 Ashley Ave. MSC 318 Charleston, SC 29425, USA
    • ,
  • A. Jason Zauls, M.D.

      Affiliations

    • Department of Radiation Oncology, Medical University of South Carolina, Hollings Cancer Center, 169 Ashley Ave. MSC 318 Charleston, SC 29425, USA
    • ,
  • Amy E. Wahlquist, M.S.

      Affiliations

    • Department of Biostatistics, Bioinformatics, Epidemiology, Medical University of South Carolina, Charleston, SC, USA
    • ,
  • Elizabeth Garrett-Mayer, Ph.D.

      Affiliations

    • Department of Biostatistics, Bioinformatics, Epidemiology, Medical University of South Carolina, Charleston, SC, USA
    • ,
  • Megan K. Baker, M.D.

      Affiliations

    • Department of Surgery, Medical University of South Carolina, Charleston, SC, USA
    • ,
  • David J. Cole, M.D.

      Affiliations

    • Department of Surgery, Medical University of South Carolina, Charleston, SC, USA
    • ,
  • Anthony E. Dragun, M.D.

      Affiliations

    • Department of Radiation Oncology, University of Louisville, James Graham Brown Cancer Center, Louisville, KY, USA
    • ,
  • Joseph M. Jenrette III, M.D.

      Affiliations

    • Department of Radiation Oncology, Medical University of South Carolina, Hollings Cancer Center, 169 Ashley Ave. MSC 318 Charleston, SC 29425, USA

Received 16 February 2009 ,Revised 11 March 2009

References 

  1. Arthur DW, Winter K, Kuske RR, et al. A Phase II trial of brachytherapy alone after lumpectomy for select breast cancer: tumor control and survival outcomes of RTOG 95–17. Int J Radiat Oncol Biol Phys. 2008;72:467–473
  2. Vicini F, Beitsch PD, Quiet CA, et al. Three-year analysis of treatment efficacy, cosmesis, and toxicity by the American Society of Breast Surgeons MammoSite Breast Brachytherapy Registry Trial in patients treated with accelerated partial breast irradiation (APBI). Cancer. 2008;112:758–66
  3. Benitez PR, Keisch ME, Vicini F, et al. Five-year results: the initial clinical trial of MammoSite balloon brachytherapy for partial breast irradiation in early-stage breast cancer. Am J Surg. 2007;194:456–462
  4. Harper JL, Jenrette JM, Vanek KN, et al. Acute complications of MammoSite brachytherapy: a single institution's initial clinical experience. Int J Radiat Oncol Biol Phys. 2005;61:169–174
  5. Team RDCR:. A Language and Environment for Statistical Computing. Vienna, Austria: R. Foundation for Statistical Computing; 2008;
  6. Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366:2087–2106
  7. Benitez PR, Streeter O, Vicini F, et al. Preliminary results and evaluation of MammoSite balloon brachytherapy for partial breast irradiation for pure ductal carcinoma in situ: a Phase II clinical study. Am J Surg. 2006;192:427–433
  8. Freedman GM, Hanlon AL, Fowble BL, et al. Recursive partitioning identifies patients at high and low risk for ipsilateral tumor recurrence after breast-conserving surgery and radiation. J Clin Oncol. 2002;20:4015–4021
  9. Arthur DW, Vicini FA, Kuske RR, et al. Accelerated partial breast irradiation: an updated report from the American Brachytherapy Society. Brachytherapy. 2002;1:184–190
  10. The American Society of Breast Surgeons. Revised consensus statement for accelerated partial breast irradiation. http://www.breastsurgeons.org/apbi.shtmlAccessed November 4, 2008.
  11. Peiro G, Bornstein BA, Connolly JL, et al. The influence of infiltrating lobular carcinoma on the outcome of patients treated with breast-conserving surgery and radiation therapy. Breast Cancer Res Treat. 2000;59:49–54
  12. Schnitt SJ, Connolly JL, Recht A, et al. Influence of infiltrating lobular histology on local tumor control in breast cancer patients treated with conservative surgery and radiotherapy. Cancer. 1989;64:448–454
  13. Chen S, Dickler A, Kirk M, et al. Patterns of failure after MammoSite brachytherapy partial breast irradiation: a detailed analysis. Int J Radiat Oncol Biol Phys. 2007;69:25–31

PII: S0002-9610(09)00236-0

doi: 10.1016/j.amjsurg.2009.03.005

The American Journal of Surgery
Volume 199, Issue 2 , Pages 204-209 , February 2010

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