The American Journal of Surgery
Volume 198, Issue 5 , Pages 611-616 , November 2009

β1-integrin mediates pressure-stimulated phagocytosis

  • Sean Bhalla

      Affiliations

    • Department of Surgery, John D. Dingell VA Medical Center, Detroit, MI, USA
    • Department of Surgery, Wayne State University, Detroit, MI, USA
    • ,
  • Hiroe Shiratsuchi, Ph.D.

      Affiliations

    • Department of Surgery, John D. Dingell VA Medical Center, Detroit, MI, USA
    • Department of Surgery, Wayne State University, Detroit, MI, USA
    • ,
  • David H. Craig, Ph.D.

      Affiliations

    • Department of Surgery, John D. Dingell VA Medical Center, Detroit, MI, USA
    • Department of Surgery, Michigan State University, 1200 E. Michigan Ave., Suite 655, Lansing, MI 48912, USA
    • ,
  • Marc D. Basson, M.D., Ph.D.

      Affiliations

    • Department of Surgery, John D. Dingell VA Medical Center, Detroit, MI, USA
    • Department of Surgery, Michigan State University, 1200 E. Michigan Ave., Suite 655, Lansing, MI 48912, USA
    • Corresponding Author InformationCorresponding author. Tel.: +1-517-267-2477; fax: +1-517-267-2488

Received 30 April 2009 ,Revised 2 July 2009

References 

  1. Schaser KD, Zhang L, Haas NP, et al. Temporal profile of microvascular disturbances in rat tibial periosteum following closed soft tissue trauma. Langenbecks Arch Surg. 2003;388:323–330
  2. Wiig H, Rubin K, Reed RK. New and active role of the interstitium in control of interstitial fluid pressure: potential therapeutic consequences. Acta Anaesthesiol Scand. 2003;47:111–121
  3. Schnall SB, Vu-Rose T, Holtom PD, et al. Tissue pressures in pyogenic flexor tenosynovitis of the finger (Compartment syndrome and its management). J Bone Joint Surg Br. 1996;78:793–795
  4. Shiratsuchi H, Basson MD. Activation of p38 MAPKalpha by extracellular pressure mediates the stimulation of macrophage phagocytosis by pressure. Am J Physiol Cell Physiol. 2005;288:C1083–C1093
  5. Basson MD, Yu CF, Herden-Kirchoff O, et al. Effects of increased ambient pressure on colon cancer cell adhesion. J Cell Biochem. 2000;78:47–61
  6. Vouyouka AG, Jiang Y, Rastogi R, et al. Ambient pressure upregulates nitric oxide synthase in a phosphorylated-extracellular regulated kinase- and protein kinase C-dependent manner. J Vasc Surg. 2006;44:1076–1084
  7. Craig DH, Owen CR, Conway WC, et al. Colchicine inhibits pressure-induced tumor cell implantation within surgical wounds and enhances tumor-free survival in mice. J Clin Invest. 2008;118:3170–3180
  8. Shiratsuchi H, Basson MD. Extracellular pressure stimulates macrophage phagocytosis by inhibiting a pathway involving FAK and ERK. Am J Physiol Cell Physiol. 2004;286:C1358–C1366
  9. Aderem A, Underhill DM. Mechanisms of phagocytosis in macrophages. Annu Rev Immunol. 1999;17:593–623
  10. Tamaki Y, Takakubo Y, Goto K, et al. Increased expression of Toll-like receptors in aseptic loose periprosthetic tissues and septic synovial membranes around total hip implants. J Rheumatol. 2009;36:598–608
  11. Taylor PR, Martinez-Pomares L, Stacey M, et al. Macrophage receptors and immune recognition. Annu Rev Immunol. 2005;23:901–944
  12. Sengelov H. Complement receptors in neutrophils. Crit Rev Immunol. 1995;15:107–131
  13. Wang QQ, Li H, Oliver T, et al. Integrin beta 1 regulates phagosome maturation in macrophages through Rac expression. J Immunol. 2008;180:2419–2428
  14. Craig DH, Gayer CP, Schaubert KL, et al. Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at threonine 788/789. Am J Physiol Cell Physiol. 2009;296:C193–C204
  15. Nilsson S, Kaniowska D, Brakebusch C, et al. Threonine 788 in integrin subunit beta1 regulates integrin activation. Exp Cell Res. 2006;312:844–853
  16. Kim M, Carman CV, Springer TA. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science. 2003;301:1720–1725
  17. Katsumi A, Naoe T, Matsushita T, et al. Integrin activation and matrix binding mediate cellular responses to mechanical stretch. J Biol Chem. 2005;280:16546–16549
  18. Knies Y, Bernd A, Kaufmann R, et al. Mechanical stretch induces clustering of beta1-integrins and facilitates adhesion. Exp Dermatol. 2006;15:347–355
  19. Eto DS, Jones TA, Sundsbak JL, et al. Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli. PLoS Pathog. 2007;3:e100
  20. Auwerx J. The human leukemia cell line, THP-1: a multifacetted model for the study of monocyte-macrophage differentiation. Experientia. 1991;47:22–31
  21. Thamilselvan V, Basson MD. Pressure activates colon cancer cell adhesion by inside-out focal adhesion complex and actin cytoskeletal signaling. Gastroenterology. 2004;126:8–18
  22. Barreuther MF, Grabel LB. The role of phosphorylation in modulating beta 1 integrin localization. Exp Cell Res. 1996;222:10–15
  23. Mulrooney JP, Hong T, Grabel LB. Serine 785 phosphorylation of the beta1 cytoplasmic domain modulates beta1A-integrin-dependent functions. J Cell Sci. 2001;114:2525–2533
  24. Wennerberg K, Fassler R, Warmegard B, et al. Mutational analysis of the potential phosphorylation sites in the cytoplasmic domain of integrin beta 1A (Requirement for threonines 788–789 in receptor activation). J Cell Sci. 1998;111:1117–1126
  25. Guyton AC, Granger HJ, Taylor AE. Interstitial fluid pressure. Physiol Rev. 1971;51:527–563
  26. Koller ME, Woie K, Reed RK. Increased negativity of interstitial fluid pressure in rat trachea after mast cell degranulation. J Appl Physiol. 1993;74:2135–2139
  27. Ostgaard G, Reed RK. Increased negatively of interstitial fluid pressure in rat skin contributes to the edema formation induced by zymosan. Microvasc Res. 1993;46:283–292
  28. Russell BH, Vasan R, Keene DR, et al. Bacillus anthracis internalization by human fibroblasts and epithelial cells. Cell Microbiol. 2007;9:1262–1274
  29. Martin P. Wound healing—aiming for perfect skin regeneration. Science. 1997;276:75–81
  30. Fowler T, Johansson S, Wary KK, et al. Src kinase has a central role in in vitro cellular internalization of Staphylococcus aureus. Cell Microbiol. 2003;5:417–426
  31. Graham IL, Anderson DC, Holers VM, et al. Complement receptor 3 (CR3, Mac-1, integrin alpha M beta 2, CD11b/CD18) is required for tyrosine phosphorylation of paxillin in adherent and nonadherent neutrophils. J Cell Biol. 1994;127:1139–1147
  32. Sindrilaru A, Peters T, Schymeinsky J, et al. Wound healing defect of Vav3-/-mice due to impaired {beta}2-integrin dependent macrophage phagocytosis of apoptotic neutrophils. Blood. 2009;113:5266–5276
  33. Pommier CG, Inada S, Fries LF, et al. Plasma fibronectin enhances phagocytosis of opsonized particles by human peripheral blood monocytes. J Exp Med. 1983;157:1844–1854
  34. Wright SD, Craigmyle LS, Silverstein SC. Fibronectin and serum amyloid P component stimulate C3b- and C3bi-mediated phagocytosis in cultured human monocytes. J Exp Med. 1983;158:1338–1343
  35. van Willigen G, Hers I, Gorter G, et al. Exposure of ligand-binding sites on platelet integrin alpha IIB/beta 3 by phosphorylation of the beta 3 subunit. Biochem J. 1996;314:769–779
  36. Dahl SC, Grabel LB. Integrin phosphorylation is modulated during the differentiation of F-9 teratocarcinoma stem cells. J Cell Biol. 1989;108:183–190
  37. Fagerholm SC, Hilden TJ, Gahmberg CG. P marks the spot: site-specific integrin phosphorylation regulates molecular interactions. Trends Biochem Sci. 2004;29:504–512
  38. O'Toole TE, Ylanne J, Culley BM. Regulation of integrin affinity states through an NPXY motif in the beta subunit cytoplasmic domain. J Biol Chem. 1995;270:8553–8558
  39. Stroeken PJ, van Rijthoven EA, Boer E, et al. Cytoplasmic domain mutants of beta1 integrin, expressed in beta 1-knockout lymphoma cells, have distinct effects on adhesion, invasion and metastasis. Oncogene. 2000;19:1232–1238

PII: S0002-9610(09)00419-X

doi: 10.1016/j.amjsurg.2009.07.006

The American Journal of Surgery
Volume 198, Issue 5 , Pages 611-616 , November 2009

Article Tools

* Image Usage & Resolution