The American Journal of Surgery
Volume 200, Issue 2 , Pages 241-246 , August 2010

Surgical treatment in Paget's disease of the breast

  • Elina Siponen, M.D.

      Affiliations

    • Breast Surgery Unit, Helsinki University Central Hospital, Helsinki, Finland
    • Corresponding Author InformationCorresponding author: Tel.: 358-40-550-93-88; fax: 358-09-47176301
    • ,
  • Katja Hukkinen, Ph.D.

      Affiliations

    • Department of Radiology, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Päivi Heikkilä, Ph.D.

      Affiliations

    • Department of Pathology, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Heikki Joensuu, Ph.D.

      Affiliations

    • Department of Oncology, Helsinki University Central Hospital, Helsinki, Finland
    • ,
  • Marjut Leidenius, Ph.D.

      Affiliations

    • Breast Surgery Unit, Helsinki University Central Hospital, Helsinki, Finland

Received 17 June 2009 ,Revised 8 July 2009

References 

  1. Kollmorgen DR, Varanasi JS, Edge SB, et al. Paget's disease of the breast. Am Coll Surg. 1998;187:171–177
  2. Kawase K, Dimaio DJ, Tucker SL, et al. Paget's disease on the breast: there is a role for breast-conserving therapy. Ann Surg Oncol. 2005;1:21–27
  3. Bijker N, Rutgers EJ, Duchateau L, et al. Breast-conserving therapy for Paget's disease of the nipple. Cancer. 2001;91:472–477
  4. Bagley FH. The role of magnetic resonance imaging mammography in the surgical management of the index breast cancer. Arch Surg. 2004;139:380–383
  5. Morrough M, Morris EA, Liberman L, et al. MRI indentifies otherwise occult disease in select patients with Paget disease of the nipple. J Am Coll Surg. 2008;206:316–321
  6. Sukumvanich P, Bentrem DJ, Cody HS, et al. The role of sentinel lymph node biopsy in Paget's disease of the breast. Ann Surg Oncol. 2007;14:1020–1023
  7. Laronga C, Nasson D, Hoover S, et al. Paget's disease in the era of sentinel lymph node biopsy. Am J Surg. 2006;192:481–483
  8. Leidenius M, Salmenkivi K, von Smitten K, et al. Tumour-positive sentinel node findings in patients with ductal carcinoma in situ. J Surg Oncol. 2006;94:380–384
  9. Chen C, Sun L, Anderson B. Paget disease of the breast: changing patterns of incidence, clinical presentation, and treatment in the U.S.. Cancer. 2006;107:1448–1458
  10. Marshall JK, Griffith KA, Haffty BG, et al. Conservative management of Paget disease of the breast with radiotherapy:10- and 15-year outcomes. Cancer. 2003;97:2142–2149
  11. Kothari AS, Beechey-Newman N, Hamed H, et al. Paget disease of the nipple: a multifocal manifestation of higher-risk disease. Cancer. 2002;95:1–7
  12. Kuhl CK, Schrading S, Bieling HB, et al. MRI for diagnosis of pure ductal carcinoma in situ: a prospective observational study. Lancet. 2007;370:485–492
  13. Frei KA, Bonel HM, Pelte MF, et al. Paget's disease of the breast: findings at magnetic resonance imaging and histopathologic correlation. Invest Radiol. 2005;40:363–367
  14. Amano G, Yajima M, Moroboshi Y, et al. MRI accurately depicts underlying DCIS in a patient with Paget's disease of the breast without palpable mass and mammography findings. Jpn J Clin Oncol. 2005;35:149–153
  15. Capobianco G, Spaliviero B, Dessole S, et al. Paget's disease of the nipple diagnosed by MRI. Arch Gynecol Obstet. 2006;274:316–318
  16. Sobin H, Wittekind C. UICC TNM classification of malignant tumours. 6th ed.. New York: John Wiley; 2002;

 This study was supported by a grant from the Helsinki University Central Hospital Research Fund (Helsinki, Finland).

PII: S0002-9610(09)00671-0

doi: 10.1016/j.amjsurg.2009.07.044

The American Journal of Surgery
Volume 200, Issue 2 , Pages 241-246 , August 2010

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