The American Journal of Surgery
Volume 199, Issue 3 , Pages 294-298 , March 2010

The utility of preoperative serum thyroid-stimulating hormone level for predicting malignant nodular thyroid disease

  • Judy Jin, M.D.

      Affiliations

    • Department of Surgery, MetroHealth Medical Center, 2500 Metrohealth Drive, Cleveland, OH 44109-1998, USA
    • ,
  • Rhoderick Machekano, Ph.D., M.P.H.

      Affiliations

    • Center for Health Care Research and Policy, MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA
    • ,
  • Christopher R. McHenry, M.D.

      Affiliations

    • Department of Surgery, MetroHealth Medical Center, 2500 Metrohealth Drive, Cleveland, OH 44109-1998, USA
    • Corresponding Author InformationCorresponding author: Tel.: +1-216-778-4753; fax: +1-216-778-3774

Received 27 July 2009 ,Revised 13 August 2009

References 

  1. Vander JB, Gaston EA, Dawber TR. The significance of nontoxic thyroid nodules (Final report of a 15-year study of the incidence of thyroid malignancy). Ann Intern Med. 1968;69:537–540
  2. Eng C. Familial papillary thyroid cancer—many syndromes, too many genes?. J Clin Endocrinol Metab. 2000;85:1755–1757
  3. Davies L, Welch HG. Increasing incidence of thyroid cancer in the United States, 1973–2002. J Am Med Assoc. 2006;295:2164–2167
  4. Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225–249
  5. Papini E, et al. Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features. J Clin Endocrinol Metab. 2002;87:1941–1946
  6. Cappelli C, Pirola I, Cumetti D, et al. Is the anteroposterior and transverse diameter ratio of nonpalpable thyroid nodules a sonographic criteria for recommending fine-needle aspiration cytology?. Clin Endocrinol (Oxf). 2005;63:689–693
  7. Boelaert K, et al. Serum thyrotropin concentration as a novel predictor of malignancy in thyroid nodules investigated by fine-needle aspiration. J Clin Endocrinol Metab. 2006;91:4295–4301
  8. Haymart MR. Understanding the relationship between age and thyroid cancer. Oncologist. 2009;14:216–221
  9. Haymart MR, et al. Higher serum TSH in thyroid cancer patients occurs independent of age and correlates with extrathyroidal extension. In: Endocrinol, C, (ed.). Oxford, 2008.
  10. Polyzos SA, et al. Serum thyrotropin concentration as a biochemical predictor of thyroid malignancy in patients presenting with thyroid nodules. J Cancer Res Clin Oncol. 2008;134:953–960
  11. Pujol P, et al. Degree of thyrotropin suppression as a prognostic determinant in differentiated thyroid cancer. J Clin Endocrinol Metab. 1996;81:4318–4323
  12. Mann K. Evaluation of risk in autonomously functioning thyroid nodules. Exp Clin Endocrinol Diabetes. 1998;106(suppl 4):S23–S26
  13. Hegedus L, Bonnema SJ, Bennedbaek FN. Management of simple nodular goiter: current status and future perspectives. Endocr Rev. 2003;24:102–132
  14. Hegedus L. Clinical practice (The thyroid nodule). N Engl J Med. 2004;351:1764–1771
  15. McHenry CR, Huh ES, Machekano RN. Is nodule size an independent predictor of thyroid malignancy?. Surgery. 2008;144:1062–1068
  16. Belfiore A, et al. Cancer risk in patients with cold thyroid nodules: relevance of iodine intake, sex, age, and multinodularity. Am J Med. 1992;93:363–369

PII: S0002-9610(09)00690-4

doi: 10.1016/j.amjsurg.2009.08.028

The American Journal of Surgery
Volume 199, Issue 3 , Pages 294-298 , March 2010

Article Tools

* Image Usage & Resolution