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Original article| Volume 72, ISSUE 2, P246-247, August 1946

Hemolytic streptococcus in wounds of rabbits

Action of 5-nitro-2-furaldehyde semicarbazone
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      Abstract

      The compound,
      The authors wish to express their appreciation to Dr. M. C. Dodd and the Eaton Laboratories for supplying the compound used in this investigation.
      The authors wish to express their appreciation to Dr. M. C. Dodd and the Eaton Laboratories for supplying the compound used in this investigation.
      5-nitro-2-furaldehyde semicarbazone, in amounts of 0.2 mg. to 10 mg. (in powdered form and in a washable base) reduced the number of group a beta hemolytic streptococci in artificially infected wounds of rabbits in a substantial number of experiments.
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      References

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        • Hubbard R.S.
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        Effects of sulfanilamide and azochloramid upon hemolytic streptococci and staphylococci in wounds of rabbits.
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        The relative efficacy of penicillin, tyrothricin, streptothricin and sulfathiazole on hemolytic streptococcus in wounds of rabbits.
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        In vitro bacteriostatic action of some simple furan derivatives.
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        Effectiveness of a nitrofuran in the treatment of infected wounds.
        Mil. Surgeon. 1945; 97: 380
      1. Dodd, M. C., Hartmann, F. W. and Ward, W. C. In preparation.