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- 1.1. The hemorrhagic diathasis following an incompatible blood transfusion reaction is associated with thrombocytopenia, prolongation of the coagulation time, prolongation of the prothrombin time, a decrease in the circulating white blood cells, the appearance of fibrinolytic activity and of a “heparinoid” anticoagulant.
- 2.(2) The reaction is somewhat different in dogs inasmuch as the fibrinogen level does not decrease as markedly as in the human case, nor does fibrinolytic activity appear.
- 3.3. It is suggested that the management of these cases be a complete immediate estimate of all the major blood clotting factors with a subsequent replacement of fibrinogen or the use of an antiheparin agent wherever indicated.
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- Blood Groups and Transfusion.Charles C Thomas, Springfield, Ill1943
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☆Aided by a grant from The Office of the Surgeon General, United States Army, Project 6-60-01-002.
© 1955 Published by Elsevier Inc.