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Scientific paper| Volume 106, ISSUE 1, P70-81, July 1963

Endocrine associated peptic ulcer

DOI:https://doi.org/10.1016/0002-9610(63)90193-4
Endocrine associated peptic ulcer
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      Abstract

      Four cases have been presented which have in common a profound ulcer diathesis occurring in association with a neoplastic endocrine lesion.
      In two subjects the adrenal gland was the site of endocrine involvement; one had hyperplasia, the other adenoma, neither showing evidence of Cushing's syndrome.
      A postulation has been made that a cause-and-effect relation exists between the adrenal lesions and the ulcers.
      Two subjects with ulcers and islet cell neoplasm corresponding to the Zollinger-Ellison syndrome are described and the reported evidence for making this a distinct syndrome discussed.
      Efforts to demonstrate a secretagogue in the plasma of subject (Case IV) and his unusual response to Norethandrolone are described and the need for further work in this area noted.
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      Article info

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      DOI: https://doi.org/10.1016/0002-9610(63)90193-4

      Copyright

      © 1963 Published by Elsevier Inc.

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