This paper is only available as a PDF. To read, Please Download here.
Fifty-eight cases of cylindroma of the head and neck region, are reviewed. The cylindroma is a small cell epithelial neoplasm with a cribriform histologic pattern. This neoplasm infiltrates widely involving almost all types of adjacent tissues, is not limited by anatomic planes, and shows marked centripetal perineural extension. Although few patients can be cured, many survive for very long periods with locally recurrent or metastatic disease. Apparent cure was seen only in six cases in which the initial excision was shown to be adequate on pathologic examination. Radiotherapy was effective in temporarily controlling local recurrence and in relieving symptoms of metastases, but did not result in long term cure in any of these patients. The duration of the disease is much longer than most other adenocarcinomas. More than half of the patients who died did so more than five years after initial therapy. Almost all local recurrences were clinically apparent within eight years, but only half of the patients with local recurrence were dead within five years of the appearance of recurrent cylindroma. No case of recurrent cylindroma was cured by either resection or radiotherapy. Distant metastases did not appear after adequate initial resection. If the primary tumor was incompletely resected the incidence of distant metastases was twice that of patients who had received only radiotherapy. Two of twelve patients with submaxillary cylindroma had associated sialolithiasis.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to The American Journal of Surgery
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Beobachtungen über Geschulste der Spercheldrusen.Arch. path. Anat. 1859; 17: 357
- Tumors of the major salivary glands.in: Atlas of Tumor Pathology. Armed Forces Institute of Pathology, Washington, D.C1954 (sec. IV, fasc. II)
- Parotid tumors, histopathology, clinical behavior and results.Surg. Gynec. & Obst. 1951; 92: 721
- Adenocarcinoma, (cylindroma type) of the parotid gland; a clinical and pathologic study of 210 cases.Surg. Gynec. & Obst. 1946; 82: 342
- Primary tumors of the submaxillary glands with special reference to the mixed tumors.Surg. Gynec. & Obst. 1942; 74: 1033
- A study of malignant tumors of a glandular nature found in the nose, throat and mouth.S. Clin. North America. 1948; 28: 1087
- A clinico pathologic study of 43 cases of glandular tumors of the tongue.Surg. Gynec. & Obst. 1959; 109: 573
- Histology, natural history and results of treatment of mucus gland tumors.Am. J. Roentgenol. 1963; 90: 1032
- Cylindromas of the upper digestive and respiratory passages—A correlative study of their histologic patterns, clinical findings and modes of therapy.Laryngoscope. 1959; 69: 1381
- A century of cylindromas.Arch. Otolaryng. 1962; 75: 364
- The histology of cylindroma of mucus gland origin.Brit. J. Cancer. 1960; 14: 612
- Cylindromas of the upper respiratory tract.J. Laryng. & Otol. 1959; 73: 722
- Tumors of salivary glands.Surg. Gynec. & Obst. 1964; 119: 1290
© 1965 Published by Elsevier Inc.