Research Article| Volume 110, ISSUE 4, P573-579, October 1965

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Localized anesthesia of the mental nerve

A significant sign of cancer of the mandible
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      Unilateral numbness of the chin and lip, without a history of trauma or extraction of a tooth, may well indicate the presence of a malignant tumor in the mandible, either from the bone itself or from adjacent or distant organs. This symptom warrants immediate thorough investigation including mandibular x-ray film, laminogram, and intraoral biopsy. External biopsy should be avoided to prevent excessive contamination of the tissue and permit subsequent successful radical surgery. A palpable intraoral mass or clearcut x-ray findings are comparatively late signs. None of the patients whose records were available in the literature and who showed inferior alveolar nerve symptoms with a palpable mass had been cured by radical surgery.
      Nine cases of inferior alveolar nerve syndrome, seven cases from the literature and two cases from a personal file, are reviewed in this paper. In one case, following the lead of numbness of the lower lip and chin and anticipation of a malignant tumor of the mandible, an intraoral biopsy was obtained and an early diagnosis of osteogenic sarcoma was made. Radical mandibulectomy was performed. To date, almost three years after surgery, the patient is alive and well without local recurrence of distant metastases.
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