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Abstract
Unilateral numbness of the chin and lip, without a history of trauma or extraction
of a tooth, may well indicate the presence of a malignant tumor in the mandible, either
from the bone itself or from adjacent or distant organs. This symptom warrants immediate
thorough investigation including mandibular x-ray film, laminogram, and intraoral
biopsy. External biopsy should be avoided to prevent excessive contamination of the
tissue and permit subsequent successful radical surgery. A palpable intraoral mass
or clearcut x-ray findings are comparatively late signs. None of the patients whose
records were available in the literature and who showed inferior alveolar nerve symptoms
with a palpable mass had been cured by radical surgery.
Nine cases of inferior alveolar nerve syndrome, seven cases from the literature and
two cases from a personal file, are reviewed in this paper. In one case, following
the lead of numbness of the lower lip and chin and anticipation of a malignant tumor
of the mandible, an intraoral biopsy was obtained and an early diagnosis of osteogenic
sarcoma was made. Radical mandibulectomy was performed. To date, almost three years
after surgery, the patient is alive and well without local recurrence of distant metastases.
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References
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© 1965 Published by Elsevier Inc.
