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Abstract
A modification of the second look protocol in which 5-fluorouracil was utilized between
the time of initial resection and second look is presented. Chemotherapy was employed
for the purpose of destroying residual foci of malignancy not recognized at the time
of the initial resection. Although the number of cases was small and the duration
of follow-up is short, it would appear that this program might be capable of preventing
tumor recurrence.
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References
- A consideration of the pathological factors influencing five-year survival in radical resection of the large bowel and rectum for carcinoma.Ann. Surg. 1947; 126: 421
- The second-look operation in the management of abdominal cancers.in: Ariel I.M. Progress in Clinical Cancer. Grune & Stratton, Inc, New York1965: 154
- Reoperation in carcinoma of the colon following resection and adjuvant chemotherapy.Surg. Gynec. & Obst. 1966; 123: 274
- Experimental evaluation of potential anticancer agents. XIII. On the criteria and kinetics associated with “curability” of experimental leukemia.Cancer Chemother. Rep. 1964; 35: 1
- Selected considerations regarding chemotherapy as adjuvant in cancer treatment.Cancer Chemother. Rep. 1966; 50: 1
- A less toxic fluorouracil dosage schedule.J.A.M.A. 1964; 190: 686
Article info
Footnotes
☆This work was supported by the National Cancer Institute, National Institutes of Health Grant CA-06749.
☆☆Presented at the Eighth Annual Meeting of the Society for Surgery of the Alimentary Tract, Atlantic City, New Jersey, June 17 and 18, 1967.
Identification
Copyright
© 1968 Published by Elsevier Inc.
