Research Article| Volume 115, ISSUE 2, P227-230, February 1968

The second look operation for carcinoma of the colon after administration of 5-fluorouracil

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      A modification of the second look protocol in which 5-fluorouracil was utilized between the time of initial resection and second look is presented. Chemotherapy was employed for the purpose of destroying residual foci of malignancy not recognized at the time of the initial resection. Although the number of cases was small and the duration of follow-up is short, it would appear that this program might be capable of preventing tumor recurrence.
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