Research Article| Volume 115, ISSUE 2, P241-246, February 1968

Preoperative radiation therapy as an adjuvant to surgery for carcinoma of the colon and rectum

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      A preliminary report has been given on 458 patients in a randomized study of the use of preoperative radiation in cancer of the sigmoid and rectum. A slightly but not significantly higher postoperative mortality has been observed in treated patients, but there has been no obvious connection with the treatment. Thus far, survival in the treated and control groups has remained the same although additional follow-up data will be necessary for final assessment.
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        • Quan S.H.
        • Deddish M.R.
        • Stearns Jr., M.W.
        The effect of preoperative roentgen therapy upon the 10 and 5 year results of the surgical treatment of cancer of the rectum.
        Surg. Gynec. & Obst. 1960; 111: 507
        • Quan S.H.Q.
        Preoperative radiation for carcinoma of the rectum.
        New York J. Med. 1966; 66: 2243
        • Stearns Jr., M.W.
        • Deddish M.R.
        • Quan S.H.
        Preoperative roentgen therapy for cancer of the rectum.
        Surg. Gynec. & Obst. 1959; 109: 225
        • Fletcher W.S.
        • Allen C.V.
        • Dunphy J.E.
        Preoperative irradiation for carcinoma of the colon and rectum.
        Am. J. Surg. 1965; 109: 77