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Abstract
The plasma activities of the acid hydrolases β-Dglucosidase and β-D-galactosidase
were studied in connection with a standardized hypotension in pigs induced by bleeding
to a mean arterial pressure of 30 mm Hg. All animals showed increases in both enzymes,
with β-glucosidase reacting most with a relative increase 6 to 73 times the preshock
values after one hour of hypovolemic shock. In prolonged hypotension, increases up
to 200 times the basal values were seen. The increases seemed to be early and correlated
with the development of irreversibility in shock, but it cannot be stated whether
the relation is causative in any respect or merely passive. The importance of concomitant
acidosis is stressed.
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Fredlund PE, Öckerman PA, Vang JO: Release of acid hydrolases during perfusion of pig liver. Acta Chir Scand in press.
Fredlund PE, Öckerman PA, Vang JO: Acidosis and increased levels of β-D-glucosidase and β-D-galactosidase after hepatic inflow occlusion in the pig. (To be published.)
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© 1972 Published by Elsevier Inc.
