Case report| Volume 124, ISSUE 3, P391-393, September 1972

The “inoperable” breast carcinoma

A successful result using zinc chloride fixative
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      Treatment of locally advanced breast carcinoma by the accepted modalities is frequently followed by local failure, acceleration of metastases, or crippling complications of the therapy itself.
      A preliminary case report is therefore made of successful local treatment utilizing a zinc chloride paste fixative. The surface of the carcinoma was thereby destroyed to a depth of about 5 mm, this dead peel being excised virtually without pain at the patient's bedside. A successive coating of fixative was then applied, and subsequently destroyed cancer excised until histologically normal tissue was reached. A skin graft to the granulating base completed the local care of the wound.
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        • Haagensen CD
        Diseases of the Breast.
        in: WB Saunders, Philadelphia1956: 534
        • Papaioannou AN
        • Urban JA
        Scalene node biopsy in locally advanced primary breast cancer of questionable operability.
        CA. 1964; 17: 1006
        • Fletcher GH
        • Montague ED
        Radical irradiation of advanced breast cancer.
        Amer J Roentgen. 1965; 93: 573
        • Edelman AH
        • Holtz S
        • Powers WE
        Rapid radiotherapy for inoperable carcinoma of the breast.
        Amer J Roentgen. 1965; 93: 585
        • AMA Subcommittee on Breast and Genital Cancer
        Androgens and estrogens in the treatment of disseminated mammary carcinoma.
        JAMA. 1960; 172: 1271
      1. JAMA. 1961; 175: 787
        • Ansfield FJ
        5-Fluorouracil for disseminated breast cancer.
        CA. 1965; 15: 226
        • Freckman HA
        • Fry HL
        • Mendez FL
        • Maurer ER
        Chlorambucil-prednisolone therapy for disseminated breast carcinoma.
        JAMA. 1964; 189: 111
        • Freckman HA
        Chemotherapy of breast cancer by regional intraarterial infusion.
        CA. 1970; 26: 560
        • Mohs FE
        New York J Med. 1968; 68: 871
        • Strauss AA
        • Appel M
        • Saphir O
        • Rabinovitz AJ
        Immunologic resistance to carcinoma produced by electrocoagulation.
        Surg Gynec Obstet. 1965; 121: 989
        • Madden JL
        • Kandalaft S
        Electrocoagulation: a primary and preferred method of treatment for cancer of the rectum.
        Ann Surg. 1967; 166: 413