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Abstract
A case of the concomitant occurrence of retractile mesenteritis and retroperitoneal
fibrosis is reported. The pathology and pathogenesis of the two conditions appear
to be identical. It is therefore suggested that the two disease processes, along with
mediastinal fibrosis, sclerosing cholangitis, Riedel's thyroiditis, and pseudotumor
of the orbit are manifestations of the same systemic disease of fibrofatty connective
tissue occurring in different locations. The etiology of systemic idiopathic fibrosis
is obscure. The most cogent theory is that it represents a hypersensitivity reaction,
possibly autoimmune in nature, to an as yet unknown antigen.
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© 1972 Published by Elsevier Inc.
