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Abstract
We retrospectively studied 20 patients with cystic fibrosis who underwent surgery
for gallbladder disease from 1973 to 1986. A long delay between the onset of symptoms
and the diagnosis was noted (mean 7.4 months). This delay was attributed to masking
of the symptoms of biliary disease by the malabsorption and pulmonary symptoms seen
in this patient population. There was a notable lack of common bile duct disease in
our patients as well as in those reported in the literature. This may have been due
to a combination of factors: the increased viscosity of the mucus, the small caliber
of the gallbladder and ductal system, and the hypotonicity of the gallbladder. We
do not recommend routine intraoperative cholangiography in patients with cystic fibrosis
and gallbladder disease.
Cystic fibrosis is a disease with progressive pulmonary deterioration. Cholecystectomy
can be performed in these patients with relative safety if careful preoperative and
postoperative care is provided. We recommend early operative intervention in the patient
with gallbladder disease and cystic fibrosis.
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References
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© 1989 Published by Elsevier Inc.
