Advertisement
Clinical paper - American| Volume 190, ISSUE 1, P9-15, July 2005

Hospitals collaborate to decrease surgical site infections

      Abstract

      Background

      Despite a large body of evidence describing care processes known to reduce the incidence of surgical site infections, many are underutilized in practice.

      Methods

      Fifty-six hospitals volunteered to redesign their systems as part of the National Surgical Infection Prevention Collaborative, a 1-year demonstration project sponsored by the Centers for Medicare & Medicaid Services. Each facility selected quality improvement objectives for a select group of surgical procedures and reported monthly clinical process measure data.

      Results

      Forty-four hospitals reported data on 35,543 surgical cases. Hospitals improved in measures related to appropriate antimicrobial agent selection, timing, and duration; normothermia; oxygenation; euglycemia; and appropriate hair removal. The infection rate decreased 27%, from 2.3% to 1.7% in the first versus last 3 months.

      Conclusions

      The Collaborative demonstrated improvement in processes known to be associated with reduced risk of surgical site infections. Quality improvement organizations can be effective resources for quality improvement in the surgical arena.

      Keywords

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Institute of Medicine Committee on Quality of Health Care in America
        Crossing the Quality Chasm.
        National Academy Press, Washington, DC2001
        • Leape L.L.
        • Lawthers A.G.
        • Brennan T.A.
        • et al.
        Preventing medical injury.
        Qual Rev Bull. 1993; 19: 144-149
        • Leape L.L.
        • Brennan T.A.
        • Laird N.
        • et al.
        The nature of adverse events in hospitalized patients.
        N Engl J Med. 1991; 324: 377-384
        • Bergamini T.M.
        • Polk Jr, H.C.
        Pharmacodynamics of antibiotic penetration of tissue and surgical prophylaxis.
        Surg Gynecol Obstet. 1989; 168: 283-289
        • Bratzler D.W.
        • Houck P.M.
        Antimicrobial prophylaxis for surgery.
        Clin Infect Dis. 2004; 38: 1706-1715
        • Classen D.C.
        • Evans R.S.
        • Pestonik S.L.
        • et al.
        The timing of prophylactic administration of antibiotics and the risk of surgical-wound infection.
        N Engl J Med. 1992; 326: 281-286
        • Dellinger E.P.
        • Gross P.A.
        • Barrett T.L.
        • et al.
        Quality standard for antimicrobial prophylaxis in surgical procedures.
        Clin Infect Dis. 1994; 18: 422-427
        • DiPiro J.T.
        • Vallner J.J.
        • Bowden Jr, T.A.
        • et al.
        Intraoperative serum and tissue activity of cefazolin and cefoxitin.
        Arch Surg. 1985; 120: 829-832
        • Fry D.E.
        • Harbrecht P.J.
        • Polk Jr, H.C.
        Systemic prophylactic antibiotics.
        Arch Surg. 1981; 116: 466-469
        • Galandiuk S.
        • Polk Jr, H.C.
        • Jagelman D.G.
        • et al.
        Re-emphasis of priorities in surgical antibiotic prophylaxis.
        Surg Gyncecol Obstet. 1989; 169: 219-222
        • Kriaras I.
        • Michalopoulos A.
        • Turina M.
        • et al.
        Evolution of antimicrobial prophylaxis in cardiovascular surgery.
        Eur J Cardiothorac Surg. 2000; 18: 440-446
      1. Mangram AJ, Horan TC, Pearson ML, et al. Guideline for prevention of surgical site infection, 1999. Hospital Infection Control Practices Advisory Committee. Infect Control Hosp Epidemiol. 1999;20:250-278; quiz 279-280. Available at: http://www.cdc.gov/ncidod/hip/ssi/ssi.pdf. Accessed January 12, 2004.

        • McDonald M.
        • Grabsch E.
        • Marshall C.
        • et al.
        Single- versus multiple-dose antimicrobial prophylaxis for major surgery.
        Aust N Z J Surg. 1998; 68: 388-396
        • Page C.P.
        • Bohnen J.M.
        • Fletcher J.R.
        • et al.
        Antimicrobial prophylaxis for surgical wounds.
        Arch Surg. 1993; 128: 79-88
        • Platt R.
        • Munoz A.
        • Stella J.
        • et al.
        Antibiotic prophylaxis for cardiovascular surgery.
        Ann Intern Med. 1984; 101: 770-774
        • Polk Jr, H.C.
        • Christmas A.B.
        Prophylactic antibiotics in surgery and surgical wound infections.
        Am Surg. 2000; 66: 105-111
        • Polk Jr, H.C.
        • Trachtenberg L.
        Antibiotic activity in surgical incisions.
        JAMA. 1980; 244: 1353-1354
        • Alexander J.W.
        • Fischer J.E.
        • Boyajian M.
        • et al.
        The influence of hair-removal methods on wound infections.
        Arch Surg. 1983; 118: 347-352
        • Allen D.B.
        • Maguire J.J.
        • Mahdavian M.
        • et al.
        Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms.
        Arch Surg. 1997; 132: 991-996
      2. Auerbach AD. Prevention of Surgical Site Infections. In: Shojania KG, Duncan BW, McDonald KM, et al, editors. Making Health Care Safer. A Critical Analysis of Patient Safety Practices. San Francisco: University of California at San Francisco-Stanford University Evidence-based Practice Center; 2001. Available at: http://www.ahrq.gov/clinic/ptsafety/pdf/chap20.pdf. Accessed January 12, 2004.

        • Dellinger E.P.
        Preventing surgical-site infections.
        Infect Control Hosp Epidemiol. 2001; 22: 604-606
        • Furnary A.P.
        • Zerr K.J.
        • Grunkemeier G.L.
        • et al.
        Continuous intravenous insulin infusion reduces the incidence of deep sternal wound infection in diabetic patients after cardiac surgical procedures.
        Ann Thorac Surg. 1999; 67: 352-360
        • Greif R.
        • Akca O.
        • Horn E.P.
        • et al.
        Supplemental perioperative oxygen to reduce the incidence of surgical-wound infection.
        N Engl J Med. 2000; 342: 161-167
        • Hopf H.W.
        • Hunt T.K.
        • West J.M.
        • et al.
        Wound tissue oxygen tension predicts the risk of wound infection in surgical patients.
        Arch Surg. 1997; 132: 997-1004
        • Horgan M.A.
        • Piatt Jr, J.H.
        Shaving of the scalp may increase the rate of infection in CSF shunt surgery.
        Pediatr Neurosurg. 1997; 26: 180-184
        • Ko W.
        • Lazenby W.D.
        • Zelano J.A.
        • et al.
        Effects of shaving methods and intraoperative irrigation on suppurative mediastinitis after bypass operations.
        Ann Thorac Surg. 1992; 53: 301-305
        • Kurz A.
        • Sessler D.I.
        • Lenhardt R.
        Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization.
        N Engl J Med. 1996; 334: 1209-1215
        • Latham R.
        • Lancaster A.D.
        • Covington J.F.
        • et al.
        The association of diabetes and glucose control with surgical-site infections among cardiothoracic surgery patients.
        Infect Control Hosp Epidemiol. 2001; 22 (607–6)
        • Melling A.C.
        • Ali B.
        • Scott E.M.
        • et al.
        Effects of preoperative warming on the incidence of wound infection after clean surgery.
        Lancet. 2001; 358: 876-880
        • Olson M.M.
        • MacCallum J.
        • McQuarrie D.G.
        Preoperative hair removal with clippers does not increase infection rate in clean surgical wounds.
        Surg Gynecol Obstet. 1986; 162: 181-182
        • Pomposelli J.J.
        • Baxter 3rd, J.K.
        • Babineau T.J.
        • et al.
        Early postoperative glucose control predicts nosocomial infection rate in diabetic patients.
        JPEN J Parenter Enter Nutr. 1998; 22: 77-81
        • Pryor K.O.
        • Fahey 3rd, T.J.
        • Lien C.A.
        • et al.
        Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population.
        JAMA. 2004; 291: 79-87
        • Sessler D.I.
        • Akca O.
        Nonpharmacological prevention of surgical wound infections.
        Clin Infect Dis. 2002; 35: 1397-1404
        • van den Berghe G.
        • Wouters P.
        • Weekers F.
        • et al.
        Intensive insulin therapy in the critically ill patients.
        N Engl J Med. 2001; 345: 1359-1367
        • Zerr K.J.
        • Furnary A.P.
        • Grunkemeier G.L.
        • et al.
        Glucose control lowers the risk of wound infection in diabetics after open heart operations.
        Ann Thorac Surg. 1997; 63: 356-361
        • Bratzler D.W.
        • Houck P.M.
        • Richards C.
        • et al.
        Use of antimicrobial prophylaxis for major surgery.
        Arc Surg. 2005; 140: 174-182
        • Kilo C.M.
        A framework for collaborative improvement.
        Qual Manag Health Care. 1998; 6: 1-13
      3. Clinical Expert Panel. Surgical Infection Prevention Collaborative Framework. Available at http://www.qualishealth.org/collabs/sip/pdfs/sipc_framework_032802a.pdf. Accessed January 12, 2004.

        • Langley G.J.
        • Nolan K.M.
        • Norman C.L.
        The Improvement Guide.
        Jossey-Bass Publishers, San Francisco1996
        • Pierce-Bulger M.
        • Nighswander T.
        Nutaqsiivik.
        Qual Manag Health Care. 2001; 9: 40-46
        • Harbarth S.
        • Samore M.H.
        • Lichtenberg D.
        • et al.
        Prolonged antibiotic prophylaxis after cardiovascular surgery and its effect on surgical site infections and antimicrobial resistance.
        Circulation. 2000; 101: 2916-2921
        • Namias N.
        • Harvill S.
        • Ball S.
        • et al.
        Cost and morbidity associated with antibiotic prophylaxis in the ICU.
        J Am Coll Surg. 1999; 188: 225-230
        • Eggimann P.
        • Pittet D.
        Infection control in the ICU.
        Chest. 2001; 120: 2059-2093
        • Velmahos G.C.
        • Toutouzas K.G.
        • Sarkisyan G.
        • et al.
        Severe trauma is not an excuse for prolonged antibiotic prophylaxis.
        Arch Surg. 2002; 137: 537-541