Abstract
Background:
Intracystic papillary carcinoma (IPC) of the breast is a rare form of noninvasive
breast cancer. An appreciation of associated pathology with IPC may be critical in
surgical decision-making.
Methods
The medical records of all patients with IPC treated between 1985 and 2001 were retrospectively
reviewed. Three patient groups were identified according to the pathologic features
of the primary tumor: IPC alone, IPC with associated ductal carcinoma in situ (DCIS),
and IPC with associated invasion with or without DCIS. Types of treatment and outcomes
were compared between groups.
Results:
Forty patients were treated for IPC during the study period. Fourteen had pure IPC,
13 had IPC with DCIS, and 13 had IPC with invasion. The incidence of recurrence and
the likelihood of dying of IPC did not differ between the three groups regardless
of the type of surgery (mastectomy or segmental mastectomy) performed and whether
radiation therapy was administered. The disease-specific survival rate was 100%.
Conclusions
When IPC is identified, it is frequently associated with DCIS and or invasion. Standard
therapy should be based on associated pathology. The role of radiation therapy in
pure IPC remains to be determined.
Keywords
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Article info
Publication history
Received in revised form:
May 27,
2002
Received:
May 6,
2002
Identification
Copyright
© 2002 Excerpta Medica Inc. Published by Elsevier Inc. All rights reserved.
