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The possibility of coagulopathy can be minimized by attending to certain general perioperative
details to avoid hypothermia, hypotension-shock, and multiple transfusions. In this
paper, we present our protocol for avoiding coagulopathy in vascular surgery. In the
past 1 1/2 years, we have used perioperative plasmapheresis in 204 patients undergoing
cardiac or aortic peripheral vascular surgery. Autologous platelet-rich plasma is
transfused at the completion of the operation after heparin reversal. Our data show
an approximate 50% reduction in homologous blood product requirement. Seventy-five
percent of patients having aortic surgery received no homologous blood products during
their hospital stay. For those undergoing cardiac surgery, there has been about a
45% reduction in the use of homologous blood products. In our experience, autologous
platelet-rich plasma not only decreases the risk of transmittable disease, but promotes
hemostasis.
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Article info
Footnotes
2Presented at the 18th Annual Meeting of the Society for Clinical Vascular Surgery, Palm Desert, California, March 7–11, 1990.
Identification
Copyright
© 1990 Reed Publishing USA. Published by Elsevier Inc.
