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Air plethysmography (APG) was used to measuremaximal venous outflow rate (MVO), a test for proximal venous obstruction; venous volume; venous filling index, an estimate of valvular incompetence; ejection fraction (EF), a test of calf-muscle pump efficiency; and residual volume fraction (RVF), an estimate of ambulatory venous pressure.
MVO was lower in patients with chronic venousinsufficiency (CVI) than in those with varicose veins (VV), but the difference was small (p=0.06). RVF was significantly greater in extremities with CVI when compared with those with VV (p <0.01). However, the degree of abnormality in venous volume, venous filling index, and EF was similar in CVI and VV extremities.
In summary, although RVF tends to be higher in extremities with CVI when compared with those with VV, there is tremendous overlap between VV and CVI for each of the hemodynamic variables measured by APC. Therefore, the pathophysiology of CVI is likely to involve not only hemodynamic abnormalities but also other factors that have not yet been clearly identified.
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**Presented at the 20th Annual Meeting of the Society for ClinicalVascular Surgery, Orlando, Florida, March 25–29, 1992.
© 1992 Reed Publishing USA. Published by Elsevier Inc.