Advertisement
Research Article| Volume 164, ISSUE 3, P260-264, September 1992

Download started.

Ok

Physiologic similarities between extremities withvaricose veins and with chronic venous insufficiency utilizing air plethysmography

  • Author Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    Paul R. Cordts
    Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    Affiliations
    Boston, Massachusetts, USA
    Search for articles by this author
  • Author Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    Choli Hartono
    Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    Affiliations
    Boston, Massachusetts, USA
    Search for articles by this author
  • Author Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    Wayne W. LaMorte
    Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    Affiliations
    Boston, Massachusetts, USA
    Search for articles by this author
  • Author Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    James O. Menzoian
    Correspondence
    Requests for reprints should be addressed to James O. Menzoian,MD, Section of Vascular Surgery, Boston University Medical Center, D-5, 88 East Newton Street, Boston, Massachusetts 02118.
    Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
    Affiliations
    Boston, Massachusetts, USA
    Search for articles by this author
  • Author Footnotes
    1 From the Sections of Vascular Surgery and Surgical Research, BostonUniversity Medical Center, Boston, Massachusetts.
      This paper is only available as a PDF. To read, Please Download here.
      Air plethysmography (APG) was used to measuremaximal venous outflow rate (MVO), a test for proximal venous obstruction; venous volume; venous filling index, an estimate of valvular incompetence; ejection fraction (EF), a test of calf-muscle pump efficiency; and residual volume fraction (RVF), an estimate of ambulatory venous pressure.
      MVO was lower in patients with chronic venousinsufficiency (CVI) than in those with varicose veins (VV), but the difference was small (p=0.06). RVF was significantly greater in extremities with CVI when compared with those with VV (p <0.01). However, the degree of abnormality in venous volume, venous filling index, and EF was similar in CVI and VV extremities.
      In summary, although RVF tends to be higher in extremities with CVI when compared with those with VV, there is tremendous overlap between VV and CVI for each of the hemodynamic variables measured by APC. Therefore, the pathophysiology of CVI is likely to involve not only hemodynamic abnormalities but also other factors that have not yet been clearly identified.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Hanrahan LM
        • Araki CT
        • Rodriguez AA
        • et al.
        Distribution of valvular incompetence in patients with venous stasis ulceration.
        J Vasc Surg. 1991; 13: 805-812
        • Christopoulos D
        • Nicolaides AN
        • Szendro G
        • et al.
        Air-plethysmography and the effect of elastic compression on venous hemodynamics of the leg.
        J Vasc Surg. 1987; 5: 148-159
        • Welkie JF
        • Comerota AJ
        • Kerr RP
        The hemodynamics of venous ulceration.
        Ann Vasc Surg. 1992; 6: 1-4
        • Nicolaides AN
        • Sumner DS
        Investigation of patients with deep vein thrombosis and chronic venous insufficiency.
        in: 1st ed. Med-Orion Publishing Co, Nicosia, Cyprus1991
        • Raju S
        • Fredericks R
        Hemodynamic basis of stasis ulceration—a hypothesis.
        J Vasc Surg. 1991; 13: 491-495
        • Hanrahan LM
        • Kechejian G
        • Cordts PR
        • et al.
        Patterns of venous insufficiency in patients with varicose veins.
        Arch Surg. 1991; 126: 687-691
        • Coleridge Smith PD
        • Scurr JH
        Current views on the pathogenesis of venous ulceration.
        in: Bergan JJ Yao JST Venous disorders. WB Saunders, Philadelphia1991: 36-51