Abstract
Background
Digital infrared thermal imaging (DITI) has resurfaced in this era of modernized computer
technology. Its role in the detection of breast cancer is evaluated.
Methods
In this prospective clinical trial, 92 patients for whom a breast biopsy was recommended
based on prior mammogram or ultrasound underwent DITI. Three scores were generated:
an overall risk score in the screening mode, a clinical score based on patient information,
and a third assessment by artificial neural network.
Results
Sixty of 94 biopsies were malignant and 34 were benign. DITI identified 58 of 60 malignancies,
with 97% sensitivity, 44% specificity, and 82% negative predictive value depending
on the mode used. Compared to an overall risk score of 0, a score of 3 or greater
was significantly more likely to be associated with malignancy (30% vs 90%, P < .03).
Conclusion
DITI is a valuable adjunct to mammography and ultrasound, especially in women with
dense breast parenchyma.
Keywords
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References
- Angiogenesis in cancer and other diseases.Nature. 2000; 407: 249-257
- A reappraisal of the use of infrared thermal image analysis in medicine.IEEE Trans Med Imaging. 1998; 17: 1019-1027
- Relationship between microvessel density and thermographic hot areas in breast cancer.Surg Today. 2003; 33: 243-248
- Breast thermography and cancer risk prediction.Cancer. 1980; 45: 51-56
- Thermography.Cancer. 1996; 77: 1324-1328
- Thermography.Cancer. 1997; 79: 186-188
- Advanced integrated technique in breast cancer thermography.J Med Eng Technol. 2008; 2: 103-114
Article info
Publication history
Received in revised form:
June 4,
2008
Received:
April 14,
2008
Footnotes
Sponsored by Infrared Sciences Corp., Bohemia, NY USA
Identification
Copyright
© 2008 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
