Abstract
Background
Antibiotic prophylaxis during placement of implanted central venous access ports (CVAP)
has not been studied. This retrospective review compared the rate of catheter-related
infections (CRIs) with and without perioperative antibiotics.
Methods
This was a single-center study that compared patients treated with and without a single
dose of antibiotics during CVAP placement. CRIs were defined as a patient treated
with antibiotics for port site induration, positive blood cultures, or suspicion of
infection that led to port removal within 30 days of placement.
Results
CVAP were placed in 459 patients, 103 of whom (22.4%) received antibiotic prophylaxis.
Surgical technique and patient demographics were similar to those patients not receiving
antibiotics (356). All 9 (2%) CRIs occurred in the non-prophylactic antibiotic group
(P = .218), with 5 infections resulting in port removal.
Conclusions
Single-dose perioperative antibiotics may decrease CVAP infection rates and should
be studied further in a prospective randomized trial.
Keywords
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Article info
Publication history
Received in revised form:
July 26,
2010
Received:
March 6,
2010
Identification
Copyright
© 2010 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
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- Unnecessary perioperative antibiotic prophylaxis in the placement of totally implanted central venous access ports should be avoidedThe American Journal of SurgeryVol. 204Issue 4
