Abstract
Background
Surgical site infection is a common complication of surgery. Its morbidities range
from delayed healing to systemic sepsis. It has impact on the economy and health care
resources.
Methods
This study was a prospective, randomized, double-blinded, controlled multicenter study
aimed to compare triclosan-coated polyglactin 910 sutures with polyglactin 910 sutures
for the reduction of surgical site infections. This article details the results from
the Cairo University center. A total of 450 patients who had undergone different surgical
procedures were enrolled; 230 were enrolled in the study group and 220 were enrolled
in the control group.
Results
The study group and the control group were comparable regarding risk factors for surgical
site infection. Surgical site infection incidence was 7% in the study group and 15%
in the control group (P = .011). The mean extended stay as a result of infection was 3.71 days, with an average
cost $91 US per day.
Conclusions
Use of the triclosan-coated polyglactin 910 antimicrobial suture lead to reduction
of surgical site infection and has an impact on saving health care resources. The
triclosan-coated polyglactin 910 antimicrobial suture could save $1,517,727 yearly
in this single center.
Keywords
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Article info
Publication history
Published online: May 20, 2011
Received in revised form:
June 21,
2010
Received:
January 5,
2010
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
