Abstract
Background
Synchronous colorectal carcinoma has seldom been studied in large series. The study
was designed to examine the significance of colorectal synchronous carcinoma in a
large cohort of patients.
Methods
The clinicopathological features of 102 patients with synchronous colorectal carcinoma
were compared with 1,793 patients with solitary colorectal carcinoma.
Results
The prevalence of synchronous colorectal carcinoma was 3.6%. In these patients, 4%
had FAP, 6% had hyperplastic polyposis, and 2% had ulcerative colitis. The index carcinoma
was more likely to have higher histological grade and T stage than other carcinoma(s)
in the same patient. When compared with solitary colorectal carcinoma, synchronous
colorectal carcinoma was more often noted in males with coexisting FAP and in proximal
location. The 5-year survival rate of patients with synchronous colorectal carcinoma
was 53% and was similar to those with solitary colorectal carcinoma.
Conclusions
We examined the clinicopathological features of patients with synchronous colorectal
carcinomas in a large cohort of patients. Attention to these features was important
for better management of this group of cancer.
Keywords
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Article info
Publication history
Published online: May 20, 2011
Received in revised form:
April 25,
2010
Received:
January 2,
2010
Identification
Copyright
© 2011 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
