Abstract
Background
Hawaii has the highest incidence of hepatocellular cancer (HCC) in the United States
and the largest proportion of Asians and Pacific Islanders. HCC studies generally
combine these groups into 1 ethnicity, and we sought to examine differences between
Asian and Pacific Islander subpopulations.
Methods
Demographic, clinical, and treatment data for 617 patients with HCC (420 Asians, 114
whites, and 83 Pacific Islanders) were reviewed. Main outcome measures included HCC
screening and liver transplantation.
Results
Asian and Pacific Islander subgroups had significantly more immigrants, and age was
different between groups. Compared with whites, Pacific Islanders and Filipinos had
less HCC screening and liver transplantation procedures, fewer met Milan criteria,
and a smaller proportion of those with Milan criteria actually underwent transplantation.
Conclusions
There were significant differences in risk factors, clinical presentation, treatment,
and access to care among Asian, Pacific Islander, and white patients with HCC. Future
HCC studies may benefit from differentiating subgroups within Asian and Pacific Islander
populations to better focus these efforts.
Keywords
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Article info
Publication history
Published online: January 09, 2012
Received in revised form:
June 3,
2011
Received:
January 27,
2011
Footnotes
This research was partially supported by American Recovery and Reinvestment Act grant 3P30CA071789-12S6.
Identification
Copyright
© 2012 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
