Abstract
Background
Hashimoto's thyroiditis is associated with decreased quality of life (QoL). Thyroid
surgery could hypothetically lead to an increase in QoL.
Methods
In a follow-up analysis of a prospective cohort study that included euthyroid women
undergoing thyroid surgery for benign thyroid disease, 248 patients were willing to
answer the SF-36 QoL questionnaire.
Results
At follow-up after a median of 26 months, only the SF-36 module of “bodily pain” had
increased (P = .046). Preoperative anti–thyroid peroxidase antibody levels were positively correlated
with increasing QoL in the SF-36 modules “bodily pain” (P < .001) and “role emotional” (P < .001). For the presence of histologically confirmed Hashimoto's thyroiditis, a
significant positive correlation (P < .001) was found for all modules apart from “physical functioning.”
Conclusions
In women with benign euthyroid goiter, thyroid surgery does not lead to an overall
improvement in health-related QoL. It should not be recommended for patients with
elevated anti–thyroid peroxidase antibody levels. Patients with histologically confirmed
Hashimoto's thyroiditis might benefit in terms of QoL.
Keywords
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Article info
Publication history
Published online: September 26, 2013
Received in revised form:
April 29,
2013
Received:
September 19,
2012
Footnotes
The authors declare no conflicts of interest.
Identification
Copyright
© 2014 Elsevier Inc. Published by Elsevier Inc. All rights reserved.
