Discussion of “Risk management decisions in women with BRCA1 and BRCA2 mutations”

Published:February 15, 2018DOI:


      • This was an analysis of treatment decisions based on genetic mutations in breast cancer.
      • The study was a retrospective review.
      • There was a higher than expected percentage of risk reduction surgery in the mutation of unknown clinical significance.
      • Patients in the Pacific Northwest chose radiographic surveillance over surgery more than other regions.
      • Surgeons must help patients understand the difference between pathogenic mutations and variants of unknown significance.
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