Highlights
- •This was an analysis of treatment decisions based on genetic mutations in breast cancer.
- •The study was a retrospective review.
- •There was a higher than expected percentage of risk reduction surgery in the mutation of unknown clinical significance.
- •Patients in the Pacific Northwest chose radiographic surveillance over surgery more than other regions.
- •Surgeons must help patients understand the difference between pathogenic mutations and variants of unknown significance.
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Article info
Publication history
Published online: February 15, 2018
Accepted:
November 22,
2017
Received:
November 22,
2017
Identification
Copyright
Published by Elsevier Inc.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Risk management decisions in women with BRCA1 and BRCA2 mutationsThe American Journal of SurgeryVol. 215Issue 5