Highlights
- •Recurrence rates of stage I and II patients with left-sided colon cancer were higher than those in the right-sided group.
- •Recurrence free survival of LCC patients was significantly shorter than that of the RCC patients.
- •In stage III patients that experienced recurrence, CSS after recurrence of the RCC was significantly shorter than that of the LCC.
Abstract
Background
Several studies have reported some differences between right-sided and left-sided
colon cancer. The aim was to analyze the differences in clinical and pathological
features, recurrence, and prognostic impact of tumor location in patients with tumors
truly located in the right and left side of the colon.
Patients
The study included 6790 stage I-III colon cancer patients who underwent curative resection.
Patient characteristics were balanced using propensity score matching.
Results
Recurrence rates of stage I and II patients with left-sided colon cancer were higher
than those in the right-sided group, indicating that recurrence free survival of left-sided
colon cancer patients was significantly shorter than that of the right-sided patients.
In stage III patients that experienced recurrence, cancer specific survival after
recurrence of the right-sided colon cancer patients was significantly shorter than
that of the left-sided patients (P = 0.003).
Conclusions
In stage I-II patients, left-sided colon cancer was a significant risk factor for
recurrence free survival, however, in stage III patients, right-sided colon cancer
was a significant risk factor for after recurrence cancer specific survival.
Keywords
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Article Info
Publication History
Published online: July 09, 2018
Accepted:
July 4,
2018
Received in revised form:
June 26,
2018
Received:
May 4,
2018
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
