Highlights
- •Among EGS patients MetS increases morbidity and hospital readmission risk.
- •MetS had the strongest negative effect on appendectomy and increased mortality.
- •Specific complications to be expected are infective, renal, and pulmonary in nature.
Abstract
Background
Metabolic syndrome (MetS) is defined by numerous comorbidities. We sought to assess
MetS’s effect on the 7 main emergency general surgery (EGS) procedures that constitute
80% of EGS procedures, mortalities, complications, and costs.
Methods
Data were acquired from the ACS-NSQIP database from 2005 to 2017. Current procedural
terminology (CPT) codes were utilized to identify cases. Patients with obesity, diabetes,
and hypertension were defined as having MetS. MetS and non-MetS cohorts were propensity
score matched, compared by outcomes, and assessed with multivariate logistic regression
to attain odds ratios (OR).
Results
Of 752,023 cases, 41,788 (5.6%) MetS cases were identified. Significant outcomes included
superficial infection (OR: 1.51), pulmonary complications (OR: 1.17), renal complications
(OR: 1.82), cumulative morbidity (OR: 1.22), and hospital readmission (OR: 1.41).
Conclusions
For patients undergoing these procedures, MetS increased risk for comorbidities and
hospital readmission. MetS had a significant impact on mortality only for appendectomy.
Keywords
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Article info
Publication history
Published online: December 21, 2019
Accepted:
December 17,
2019
Received in revised form:
December 1,
2019
Received:
June 26,
2019
Identification
Copyright
© 2019 Elsevier Inc. All rights reserved.