Highlights
- •Combining TI-RADS score with Bethesda diagnostic grouping allows for more accurate preoperative thyroid nodule ROM estimation.
- •TI-RADS score of 5 increases the ROM estimation for thyroid nodules with any Bethesda diagnosis.
- •For Bethesda diagnostic groupings less than VI, the TI-RADS score was more predictive of ROM.
Abstract
Background
We sought to determine if using the ACR TI-RADS ultrasound score combined with the
Bethesda diagnosis can help augment thyroid cancer risk estimation.
Methods
TI-RADS scores and Bethesda diagnoses were collected for patients treated in our center
who had undergone thyroidectomy. Data from 186 patients with both TI-RADS scores and
Bethesda diagnosis, and Bethesda diagnosis alone, were analyzed by multivariable regression
analysis and observed for whether the pathology was benign or malignant.
Results
The regression analysis model showed that as the TI-RADS score increases, the odds
of malignancy increases as well. The predictive value of the odds of malignancy in
a thyroid nodule using both Bethesda diagnosis and TI-RADS score together was more
powerful than the odds given using the Bethesda diagnosis alone.
Conclusions
Our model shows that the ACR TI-RADS score may assist with preoperative decision-making
for patients with cytologically indeterminate thyroid nodules when combined with Bethesda
diagnosis.
Keywords
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Article info
Publication history
Published online: March 02, 2022
Accepted:
February 25,
2022
Received in revised form:
January 18,
2022
Received:
November 10,
2021
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
