The incidence of differentiated thyroid cancer (DTC) has increased sharply in high-income
countries over the last few decades; however, prognosis remains excellent, with 5-year
survival rates above 95% even with regional disease spread. Health-related quality
of life (HRQOL) is therefore a critical outcome measure in DTC, as complications from
treatment can result in lifelong morbidity. Understanding factors that HRQOL after
surgery can guide patient-centered care, from decisions on surgical extent to provision
of resources to optimize patients’ postoperative psychosocial well-being, and enable
further refinement of current HRQOL assessment tools. Existing tools to measure HRQOL
include general or disease-specific domains of well-being. The validated THYCA-QoL
assessment focuses on common symptoms caused by thyroid cancer and its treatment,
including voice changes, hypocalcemia-related complaints, mood disturbances, and fatigue.
1
Yet, additional factors not captured in the assessment may modulate the subjective
experience of these symptoms and independently affect HRQOL.To read this article in full you will need to make a payment
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Article info
Publication history
Published online: May 29, 2022
Accepted:
May 22,
2022
Received in revised form:
April 29,
2022
Received:
January 10,
2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
