Cholecystectomy prior to short bowel syndrome does not alter nutritional prognosis


      • Cholecystectomy is common in short bowel syndrome (SBS) patients.
      • Cholecystectomy in SBS patients increases the risk of liver fibrosis/cirrhosis.
      • Cholecystectomy prior to development of SBS does not alter need for chronic parenteral nutrition.
      • This effect is not influenced by intestinal length or anatomy.



      Previous cholecystectomy is common in patients with short bowel syndrome (SBS). An intact gallbladder is beneficial in preventing cirrhosis in SBS patients, but the nutritional consequences of cholecystectomy are largely unknown. Our aim was to evaluate the effect of pre-SBS cholecystectomy on need for chronic parenteral nutrition (PN).


      We reviewed 485 adults with SBS: 267 underwent cholecystectomy prior to SBS and 218 patients had an intact gallbladder. Demographic data, intestinal anatomy, and nutritional outcome were compared.


      Pre-SBS cholecystectomy patients were more likely to have had postoperative SBS and BMI >35. Intestinal remnant length and anatomy type and performance of surgical rehabilitation procedures within the first year were similar.
      Overall, there was no significant difference in the need for PN > 1year between the two groups. There was also no significant difference in the need for PN > 1year in any specific subgroup of intestinal remnant length or intestinal anatomy.


      Cholecystectomy performed prior to the development of SBS does not influence the nutritional prognosis of SBS, regardless of the intestinal remnant length and anatomy type.


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