Highlights
- •Cholecystectomy is common in short bowel syndrome (SBS) patients.
- •Cholecystectomy in SBS patients increases the risk of liver fibrosis/cirrhosis.
- •Cholecystectomy prior to development of SBS does not alter need for chronic parenteral nutrition.
- •This effect is not influenced by intestinal length or anatomy.
Abstract
Background
Previous cholecystectomy is common in patients with short bowel syndrome (SBS). An
intact gallbladder is beneficial in preventing cirrhosis in SBS patients, but the
nutritional consequences of cholecystectomy are largely unknown. Our aim was to evaluate
the effect of pre-SBS cholecystectomy on need for chronic parenteral nutrition (PN).
Methods
We reviewed 485 adults with SBS: 267 underwent cholecystectomy prior to SBS and 218
patients had an intact gallbladder. Demographic data, intestinal anatomy, and nutritional
outcome were compared.
Results
Pre-SBS cholecystectomy patients were more likely to have had postoperative SBS and
BMI >35. Intestinal remnant length and anatomy type and performance of surgical rehabilitation
procedures within the first year were similar.
Overall, there was no significant difference in the need for PN > 1year between the
two groups. There was also no significant difference in the need for PN > 1year in
any specific subgroup of intestinal remnant length or intestinal anatomy.
Conclusions
Cholecystectomy performed prior to the development of SBS does not influence the nutritional
prognosis of SBS, regardless of the intestinal remnant length and anatomy type.
Keywords
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Article Info
Publication History
Published online: June 23, 2022
Accepted:
June 20,
2022
Received in revised form:
June 2,
2022
Received:
January 6,
2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
