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Low Volume Blood Product Transfusion Patterns And Ratios After Injury

      Highlights

      • Low Volume Blood Product Transfusion Patterns And Ratios After Injury: Highlights.
      • Platelet & plasma transfusion ratios were more balanced at low volume transfusions.
      • Transfusion ratios were increasingly unbalanced in high volume transfusions.
      • The ideal transfusion ratio in low volume trauma resuscitation is unknown.

      Abstract

      Background

      The benefit of a balanced resuscitation in low volume transfusions remains unclear This study is aimed at characterizing blood product ratios in this cohort.

      Methods

      A retrospective analysis (2017–2019) of the ACS TQIP was performed to identify adult trauma patients who received ≥1 unit of packed red blood cells (pRBCs) 4 and 24 h after admission. Blood products received were used to calculate plasma and platelet ratios.

      Results

      Plasma and platelet ratios were closer to the target 1:1 ratio for ≤4 units pRBCs. Plasma and platelet ratios increased for those receiving ≤10 units pRBCs, demonstrating increasingly unbalanced resuscitation. Transfusion ratios were unbalanced for those receiving ≥5 units pRBC.

      Conclusion

      Transfusion ratios were closer to the desired transfusion ratio for low volume blood product resuscitation. In those receiving ≥5 units pRBC, plasma and platelet ratios were not balanced. The optimal transfusion ratio in low volume trauma resuscitation is unknown.

      Graphical abstract

      Keywords

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