Highlights
- •Frey procedure is associated with acceptable perioperative morbidity and a low mortality.
- •Postoperative major complications developed in 12% of patients.
- •Duration of CP & blood transfusions were independent predictors of postoperative complications.
Abstract
Background
The literature on predictors for postoperative complications after Frey procedure
(FP) is sparse. The aim of this study is to report our experience with 90-day complications
of FP and predictors for complications.
Methods
All patients with chronic pancreatitis (CP), who underwent a FP between August 2007
and July 2021, were retrospectively reviewed. Univariate and multivariate analysis
were used to identify predictors of 90-day morbidity and mortality.
Results
Of the total 270 patients, 84 (31%) patients developed at least one postoperative
complication. Major complications occurred in 32 (12%) patients. Most common complication
was wound infection and it was significantly more common in stented patients (p = 0.017).
Pancreatic fistula and post pancreatectomy hemorrhage (PPH) developed in 7.4% of patients.
Thirteen patients (4.8%) required early re-operation and the most common cause of
re-exploration was PPH. 90-day mortality was 1% (n = 3) and all 3 patients required
re-exploration for PPH. Median postoperative hospital stay was 9 (5–51) days. Perioperative
blood transfusions was the only independent predictor of postoperative complications
after FP.
Conclusions
Frey procedure is an acceptable treatment modality with low rates of mortality and
reasonable perioperative morbidities. Minimizing blood transfusions may further improve
90-day outcomes.
Keywords
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Article info
Publication history
Published online: October 12, 2022
Accepted:
October 9,
2022
Received in revised form:
October 4,
2022
Received:
August 12,
2022
Publication stage
In Press Journal Pre-ProofIdentification
Copyright
© 2022 Elsevier Inc. All rights reserved.
