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Emergent colectomy for colorectal cancer: A comparative analysis of open vs. minimally invasive approach

Published:October 14, 2022DOI:https://doi.org/10.1016/j.amjsurg.2022.10.019

      Highlights

      • Minimally invasive colectomy approach for CRC is associated with longer operative times compared to open surgical approach in emergent settings.
      • Minimally invasive colectomy approach for CRC is associated with lower 30-day mortality and 30-day complications.
      • Minimally invasive colectomy approach in the emergency setting may have the potential to improve patient outcomes and decrease the burden of healthcare cost.

      Abstract

      Introduction

      Emergent surgery for colorectal cancer (CRC) is associated with higher rates of morbidity and mortality and outcomes differ by surgical approach.

      Methods

      Our study compares short-term surgical outcomes of patients undergoing emergent colectomy for CRC using the open vs minimally invasive (MIS) approach. We performed a four-year review (2012–2015) of the ACS-NSQIP Colectomy dataset and included all adult patients with CRC who underwent emergent surgical intervention. Patients were stratified into groups based on surgical approach: Open and MIS (including laparoscopic and robotic).

      Results

      A total of 1855 (MIS: 279, Open: 1576) patients were included. Outcome measures were operative time, 30-day complications, 30-day readmission, and 30-day mortality. Multivariate Regression analysis was performed. Patients in the open group were more likely to be older (70y vs. 61y, p < 0.01), have higher ASA class, and were less likely to have received mechanical bowel preparation. On univariate analysis, patients in the MIS group had longer operative time (189 ± 41 min vs. 161 ± 69 min, p < 0.01). Patients in the open group had higher rates of mortality (6.7% vs. 3.8%, p < 0.01) and 30-day complications (28.1% vs. 16.7%, p < 0.01). On regression analysis, the open approach was independently associated with higher odds of 30-day mortality and 30-day complications.

      Conclusion

      Given the lower overall mortality and complications, MIS colectomy may be a safer approach in the emergent treatment of patients with colorectal cancer.

      Keywords

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