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Original Research Article|Articles in Press

Short and long-term oncologic outcomes of patients with colon cancer of the splenic flexure

Published:February 06, 2023DOI:https://doi.org/10.1016/j.amjsurg.2023.02.005

      Highlights

      • The overall and recurrence-free survival in patients with segmental and anatomical colon resection are not different.
      • Anatomical resection has higher lymph node yield.
      • Higher age and tumor stage correlate with higher mortality.
      • Positive margins are associated with decreased recurrence free survival.

      Abstract

      Background

      There is currently no consensus on surgical management of splenic flexure adenocarcinoma (SFA).

      Methods

      Patients undergoing surgical resection for SFA between 1993 and 2015 were identified. Postoperative outcomes were compared between patients who underwent segmental (SR) vs. anatomical resection (AR).

      Results

      One-hundred and thirteen patients underwent SR and 89 underwent AR. More patients in the SR group had open resections, but there were otherwise no differences in demographics or surgical characteristics between the two groups. There were no differences in overall (p = 0.29) or recurrence-free(p = 0.37) survival. On multivariable analysis, increased age (HR 1.04, 1.01–1.07, p = 0.005), higher American Society of Anesthesiology classification (HR 3.1, 1.7–5.71, p < 0.001), and higher tumor stage (HR 8.84, 3.76–20.82, p < 0.001) were predictive of mortality.

      Conclusions

      Short and long-term outcomes after SR and AR for SFA are not different, making SR a viable option for SFA surgical management.

      Keywords

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